Purification and characterization of an α-actinin-binding PDZ-LIM protein that is up-regulated during muscle differentiation

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Publication Type journal article
School or College College of Science
Department Biology
Creator Beckerle, Mary C.
Other Author Pomiès, Pascal; Macalma,Teresita
Title Purification and characterization of an α-actinin-binding PDZ-LIM protein that is up-regulated during muscle differentiation
Date 1999
Description α-Actinin is required for the organization and function of the contractile machinery of muscle. In order to understand more precisely the molecular mechanisms by which α-actinin might contribute to the formation and maintenance of the contractile apparatus within muscle cells, we performed a screen to identify novel α-actinin binding partners present in chicken smooth muscle cells. In this paper, we report the identification, purification, and characterization of a 36-kDa smooth muscle protein (p36) that interacts with α-actinin.
Type Text
Publisher American Society for Biochemistry and Molecular Biology (ASBMB)
Volume 274
Issue 41
First Page 29242
Last Page 29250
Subject LIM domains; Z-disc; Actin; Actinin-associated LIM proteins; PDZ-LIM protein
Subject LCSH Muscle proteins; Muscle cells; Muscle contraction; Facioscapulohumeral muscular dystrophy
Language eng
Bibliographic Citation Pomiès, P., Macalma,T., & Beckerle, M. C. (1999). Purification and characterization of an α-actinin-binding PDZ-LIM protein that is up-regulated during muscle differentiation. Journal of Biological Chemistry, 274(41), 29242-50.
Rights Management (c)American Society for Biochemistry and Molecular Biology (ASBMB) http://www.asbmb.org/
Format Medium application/pdf
Format Extent 1,117,650 bytes
Identifier ir-main,6522
ARK ark:/87278/s6j96qgt
Setname ir_uspace
ID 702537
Reference URL https://collections.lib.utah.edu/ark:/87278/s6j96qgt
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