Publication Type |
journal article |
School or College |
College of Science |
Department |
Biology |
Creator |
Beckerle, Mary C. |
Other Author |
Pomiès, Pascal; Macalma,Teresita |
Title |
Purification and characterization of an α-actinin-binding PDZ-LIM protein that is up-regulated during muscle differentiation |
Date |
1999 |
Description |
α-Actinin is required for the organization and function of the contractile machinery of muscle. In order to understand more precisely the molecular mechanisms by which α-actinin might contribute to the formation and maintenance of the contractile apparatus within muscle cells, we performed a screen to identify novel α-actinin binding partners present in chicken smooth muscle cells. In this paper, we report the identification, purification, and characterization of a 36-kDa smooth muscle protein (p36) that interacts with α-actinin. |
Type |
Text |
Publisher |
American Society for Biochemistry and Molecular Biology (ASBMB) |
Volume |
274 |
Issue |
41 |
First Page |
29242 |
Last Page |
29250 |
Subject |
LIM domains; Z-disc; Actin; Actinin-associated LIM proteins; PDZ-LIM protein |
Subject LCSH |
Muscle proteins; Muscle cells; Muscle contraction; Facioscapulohumeral muscular dystrophy |
Language |
eng |
Bibliographic Citation |
Pomiès, P., Macalma,T., & Beckerle, M. C. (1999). Purification and characterization of an α-actinin-binding PDZ-LIM protein that is up-regulated during muscle differentiation. Journal of Biological Chemistry, 274(41), 29242-50. |
Rights Management |
(c)American Society for Biochemistry and Molecular Biology (ASBMB) http://www.asbmb.org/ |
Format Medium |
application/pdf |
Format Extent |
1,117,650 bytes |
Identifier |
ir-main,6522 |
ARK |
ark:/87278/s6j96qgt |
Setname |
ir_uspace |
ID |
702537 |
Reference URL |
https://collections.lib.utah.edu/ark:/87278/s6j96qgt |