| Title |
Pancreatic Neuroendocrine Paraneoplastic Optic Neuropathy: Confirmation with Antibody to Optic Nerve and Hepatic Metastasis |
| Creator |
Slamovits, Thomas L; Posner, Jerome B; Reidy, Diane L; Thirkill, Charles E; Keltner, John L |
| Affiliation |
Department of Ophthalmology, Neurology and Neurosurgery, Albert Einstein College of Medicine, Bronx, New York; Department of Neurology, Memorial Sloan-Kettering Cancer Center, New York, New York; Department of Medicine, Memorial Sloan-Kettering Cancer Center, New York, New York; Ocular Immunology Laboratory, Department of Ophthalmology and Vision Science, University of California Davis, Davis, California; and Department of Ophthalmology and Vision Science, Neurology and Neurosurgery, University of California Davis Medical Center, Sacramento, California |
| Abstract |
A 68-year-old woman presented with bilateral visual loss as the only clinical manifestation of an occult pancreatic nonsecretory neuroendocrine tumor (NET). The suspected diagnosis of paraneoplastic optic neuropathy was confirmed using immunofluorescence assays to demonstrate the presence of antibodies in the patient's serum that reacted with antigen(s) in the optic nerve and in the pancreatic NET hepatic metastasis. Treatment of the underlying cancer was followed by marked improvement in visual function. |
| Subject |
Older people; Female; Humans; Neuroendocrine Tumors; Optic Nerve; Optic Nerve Diseases; Pancreatic Neoplasms; Paraneoplastic Syndromes, Ocular; Vision Disorders; Visual Acuity |
| Format |
application/pdf |
| Publication Type |
Journal Article |
| Collection |
Neuro-Ophthalmology Virtual Education Library: Journal of Neuro-Ophthalmology Archives: https://novel.utah.edu/jno/ |
| Publisher |
Lippincott, Williams & Wilkins |
| Holding Institution |
Spencer S. Eccles Health Sciences Library, University of Utah |
| Rights Management |
© North American Neuro-Ophthalmology Society |
| Setname |
ehsl_novel_jno |
| ID |
227413 |
| Reference URL |
https://collections.lib.utah.edu/ark:/87278/s6r81m9z/227413 |
