| Title |
Up-Down Asymmetry of Saccadic Contrapulsion in Lateral Medullary Syndrome |
| Creator |
Kaski, Diego; Bentley, Paul; Lane, Russell; Bronstein, Adolfo |
| Affiliation |
Imperial College London, Charing Cross Hospital, London, United Kingdom |
| Abstract |
We report greater amplitude of horizontal contrapulsion on upward vs. downward vertical saccades in a patient with saccadic contrapulsion as a result of a focal demyelinating lesion of the left dorsolateral medulla. The vertical asymmetry in horizontal saccadic contrapulsion likely relates to an imbalance of fastigial oculomotor inputs on horizontal burst neurons during vertical saccades as reported in nonhuman primates. Our finding suggests that such asymmetry is also present in humans and provides insight into the pathophysiology of saccade generation. |
| Subject |
Adult; Humans; Lateral Medullary Syndrome; Magnetic Resonance Imaging; Male; Ocular Motility Disorders; Oligoclonal Bands; Saccades |
| Format |
application/pdf |
| Publication Type |
Journal Article |
| Collection |
Neuro-Ophthalmology Virtual Education Library: Journal of Neuro-Ophthalmology Archives: https://novel.utah.edu/jno/ |
| Publisher |
Lippincott, Williams & Wilkins |
| Holding Institution |
Spencer S. Eccles Health Sciences Library, University of Utah |
| Rights Management |
© North American Neuro-Ophthalmology Society |
| Setname |
ehsl_novel_jno |
| ID |
227322 |
| Reference URL |
https://collections.lib.utah.edu/ark:/87278/s61v8m1c/227322 |
