| Title |
Downbeat nystagmus with phenytoin. |
| Creator |
Berger, J.R.; Kovacs, A.G. |
| Abstract |
Downbeat nystagmus is generally the result of a structural lesion at the craniocervical junction. It has rarely been reported as a manifestation of metabolic disease or drug intoxication. We observed two patients with downbeat nystagmus secondary to phenytoin (Dilantin) intoxication. Both individuals had other features of phenytoin-induced central nervous system dysfunction with toxic blood levels of the drug (greater than 20 micrograms/ml). Complete resolution of the downbeat nystagmus followed the return of phenytoin levels to the therapeutic range. |
| Subject |
Adult; Ataxia; Central Nervous System Diseases; Female; Humans; Male; Middle Older people; Nystagmus, Pathologic; Phenytoin; Seizures |
| Format |
application/pdf |
| Publication Type |
Journal Article |
| Collection |
Neuro-Ophthalmology Virtual Education Library: Journal of Neuro-Ophthalmology Archives: https://novel.utah.edu/jno/ |
| Publisher |
Lippincott, Williams & Wilkins |
| Holding Institution |
Spencer S. Eccles Health Sciences Library, University of Utah |
| Rights Management |
© North American Neuro-Ophthalmology Society |
| Setname |
ehsl_novel_jno |
| ID |
226912 |
| Reference URL |
https://collections.lib.utah.edu/ark:/87278/s6h73mwt/226912 |
