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Show LITERATURE ABSTRACTS 301 Temporal Artery Biopsies: Correlation of Light Microscopy and Immunofluorescence Microscopy. Wells KK, Folberg R, Goeken JA, Kemp JD. Ophthalmology 1989; 96: 1058- 64 Guly). [ Reprint requests to Dr. R. Folberg, Eye Pathology Laboratory, Room 233 MRC, University of Iowa, Iowa City, IA 52242.] The authors studied 100 consecutive temporal artery biopsy specimens with direct immunofluorescence microscopy ( DIFM) and found a high correlation with biopsy positive by light microscopy for arteritis and DIFM. Only 14 biopsies were positive for arteritis, 13 of which showed some DIFM; however, five more patients were felt to have temporal arteritis but had a negative biopsy by light microscopy, and only one of these five had a weakly positive DIFM. The authors do note the features of their study that are improvements to other similar studies, but they conclude that DIFM adds little to the diagnostic capability of light microscopy in temporal arteritis. Lyn A. Sedwick, M. D. T- lymphocyte Subpopulations in Acute Unilateral Optic Neuritis. Guy JR, Feldberg NT, Savino PR, Schatz N], Sergott RC. Ophthalmology 1989; 96: 1054- 7 Guly). [ Reprint requests to Dr. J. R. Guy, Neuro- ophthalmology Service, Box J- 284 JHMHC, University of Florida, College of Medicine, Gainesville, FL 32610- 0284.] The authors measured T- cell subsets in patients with acute optic neuritis but with no history of multiple sclerosis. The results were indistinguishable statistically from normal controls, even in the one patient in the study who did develop multiple sclerosis. Although T- cell ratios have been found to be abnormal in patients with multiple sclerosis, apparently this ratio is not disordered in patients with isolated optic neuritis. Discussion centers on possible reasons for a normal ratio in these patients. Lyn A. Sedwick, M. D. Intracranial Aneurysms with Superior Division Paresis of the Oculomotor Nerve. Guy JR, Day AL. Ophthalmology 1989; 96: 1071- 6 Guly). [ Reprint requests to Dr. J. R. Guy, Neuro- ophthalmology Service, Box J- 284, JHMHC, University of Florida, College of Medicine, Gainesville, FL 32610- 0284.) Drs. Guy and Day report five cases of pupilsparing superior division third nerve palsies in which cerebral aneurysm was directly or indirectly ( brainstem infarct) causative. Basilar artery aneurysm was present in three, superior cerebellar artery aneurysm in one, and intracavernous carotid aneurysm in one. In all patients, computerized tomographic scanning was abnormal, and was followed by angiography. Thus, although the authors conclude that angiography is required for all patients with superior division third nerve palsy, perhaps computerized tomographic investigation is required with angiography following that if deemed necessary. Lyn A. Sedwick, M. D. Optic Tract Injury after Anterior Temporal Lobectomy. Anderson DR, Trobe JD, Hood TW, Gebarski SS. Ophthalmology 1989; 96: 1065- 70 ( July). [ Reprint requests to Dr. J. D. Trobe, University of Michigan Medical Center, Department of Ophthalmology, W. K. Kellogg Eye Center, 1000 Wall St., Ann Arbor, MI 48105.) Three cases are presented in which homonymous hemianopia attributable to optic tract injury, probably infarction, occurred after temporallobectomy done for seizures. Excellent optic nerve photographs, magnetic resonance images, anatomic drawings of pertinent blood supply, and a handy table comparing the two most common optic tract syndromes make this article a jewel. Lyn A. Sedwick, M. D. Retroviruses and Their Play- pals. Beauvais DA, Michelson JB, Seybold JE, Friedlaender MH, Boyden DG. Comments by Newman S, Benson WE, Sedwick L. Surv Ophthalmol 1989; 34: 59- 64 GulyAug). [ Reprint requests to Dr. J. B. Michelson, Division of Ophthalmology, Scripps Clinic and Research Foundation, 10666 North Torrey Pines Road, La Jolla, CA 92037.) This clinical- pathological conference article concerns a 28- year- old man with uveitis and optic neuritis. He was found to have positive serology and J Clin Neuro- o/, hthalmol, Vol. 10. No. 4. 1990 |