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Show ! Dumal of Clinical N~ uro- ophthalmologll 12( 3): 213- 217. 1992. Literature Abstracts Management and Monitoring of Cancer- Associated Retinopathy. Keltner JL, Thirkill CE, Tyler NK, Roth AM. Arch Ophtizallllol 1992; 110: 48- 53 ( Jan). [ Reprint requests to Dr. J. L. Keltner, Department of Ophthalmology, University of California, Davis, Medical Center, 1603 Alhambra Blvd., Sacramento, CA 95816.) The authors describe an 86- year- old man with a 35- year history of smoking who presented with visual loss. Computed tomographic scanning of brain and orbits was normal. Electroretinography became flat within several months, and 1 month following his visual loss small cell carcinoma of the lung was diagnosed. Serum antibodies to the retina were detected but were not greatly elevated initially. Several months later, serum antibodies were found to be more elevated in association with clinical worsening of visual function; thus prednisone therapy was begun. Subsequent antibody determination showed a decline. The authors argue that antibody determination in this patient helped guide therapeutic intervention. LYII A. Sedwick, M. D. The Pattern Visual Evoked Potential and Pattern Electroretinogram in Drusen- Associated Optic Neuropathy. Scholl GB, Song HS, Winkler DE, Wray SH. Arch Ophthalmol 1992; 110: 75- 81 ( Jan). [ Reprint requests to Dr. G. B. Scholl, Unit for Neurovisual Disorders, ACC 837, Massachusetts General Hospital, 15 Parkman St., Boston, MA 02114.) Sixteen patients, 26 eyes, with optic nerve drusen were subjected to pattern visual evoked potential and pattern electroretinography. Their results suggest that abnormalities can be detected in these tests even without significant visual loss with optic nerve drusen. LYII A. Sedwick, M. D. 213 <[;, 1992 Raven Press, Ltd .. New York Visual Dysfunction Without Retinitis in Patients With Acquired Immunodeficiency Syndrome. Quiceno JI, Capparelli E, Sadun AA, Munguia 0, Grant I, Listhaus A, Crapotta J, Lambert B, Freeman WR. Am J OphthalllloI1992; 113:~ 13 ( Jan). [ Reprint requests to Dr. W. R. Freeman, Shiley Eye Center, 0946, University of California San Diego, La Jolla, CA 92093.) Morphometric Comparisons of Optic Nerve Axon Loss in Acquired Immunodeficiency Syndrome. Tenhula WN, Shizao X, Madigan Me, Heller K, Freeman WR, Sadun AA. Am J Ophthalmol 1992; 113: 14- 20 ( Jan). [ Reprint requests to Dr. A. A. Sadun, Doheny Eye Institute, 1355 San Pablo St., Los Angeles, CA 90033.) In the first article, the authors studied 78 patients ( 156 eyes) with acquired immunodeficiency syndrome ( AIDS) and found defects of color vision and contrast sensitivity even without florid retinopathy. They postulate that a primary optic neuropathy may occur with AIDS or with a human immunodeficiency virus ( HIV)- related process. The second paper describes optic nerve axonal loss at autopsy of AIDS patients, which supports the hypothesis of a primary optic neuropathy with AIDS. LYII A. Sedwick, M. D. Severe Periphlebitis, Peripheral Retinal Ischemia, and Preretinal Neovascularization in Patients With Multiple Sclerosis. Vine AK. Am J Ophthal11101 1992; 113: 2~ 32 ( Jan). [ Reprint requests to Dr. A. K. Vine, Retina Service, W. K. Kellogg Eye Center, University of Michigan, 1000 Wall St., Ann Arbor, MI 48105.] Two patients with multiple sclerosis developed periphlebitis and retinal ischemia. One had initial mild uveitis and the other subsequently developed a granulomatous uveitis. Extensive testing for |