The sleep test for myasthenia gravis. A safe alternative to Tensilon.

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Title Journal of Neuro-Ophthalmology, December 1991, Volume 11, Issue 4
ARK ark:/87278/s6p30463
Setname ehsl_novel_jno
Date Created 2010-12-14
Date Modified 2010-12-14
ID 226044
Reference URL https://collections.lib.utah.edu/ark:/87278/s6p30463

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Title The sleep test for myasthenia gravis. A safe alternative to Tensilon.
Creator Odel, J.G.; Winterkorn, J.M.; Behrens, M.M.
Affiliation E.S. Harkness Eye Institute, Columbia-Presbyterian Medical Center, New York, New York.
Subject Blepharoptosis; Child; Edorphonium; Female; Humans; Male; Middle Aged; Myasthenia Gravis; Ophthalmoplegia; Sleep
Abstract The diagnosis of myasthenia gravis is usually confirmed by a Tensilon test, which can be complicated by cholinergic side effects that include cardiopulmonary arrest. An alternative, the Sleep test, based on the characteristic of myasthenia that symptoms and signs worsen with fatigue and improve after a period of rest, is safe, moderately sensitive, and specific. The diagnosis of myasthenia can be confirmed by observing resolution of ptosis or ophthalmoparesis immediately after a 30-minute period of sleep; the reappearance of the myasthenic signs over the next 30 seconds to 5 minutes adds further confirmation.
OCR Text Show
Publisher Lippincott, Williams & Wilkins
Date 1991-12
Type Text
Rights Management © North American Neuro-Ophthalmology Society
Publication Type Journal Article
Setname ehsl_novel_jno
Date Created 2010-12-14
Date Modified 2010-12-14
ID 226038
Reference URL https://collections.lib.utah.edu/ark:/87278/s6p30463/226038