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Show 290 LITERATURE ABSTRACTS AdlerJS, RootmanJ. Arch OphthalmoI1993;111:81923 Gun). [Reprint requests to Dr. J. Rootman, Department of Ophthalmology, University of British Columbia, 2550 Willow St, Vancouver, British Columbia, Canada V5Z 3N9.] The authors recalled 21 patients who had orbital radiation therapy at least one year previously and compared their computerized tomographic and clinical findings to six "clinically comparable" patients who had not had radiation therapy. They found no significant computed tomographic differences between the groups; and clinical signs, especially soft tissue, were improved in both groups. They conclude that "the benefits of orbital XRT should be seen, at best, as an improvement of softtissue signs, not long-term change in radiologic parameters of muscle size." One may wish to challenge this study on several points, not the least of which being their contention that "(I)n most centers, the indication for orbital XRT is the management of severe soft-tissue signs in patients with acute, active disease." Lyn A. Sedwick, M.D. A Screening Test for Integrative Visual Dysfunction in Alzheimer's Disease. Trobe JD, Butter CM. Arch Ophthalmol 1993;111:815-8 Gun). [Reprint requests to Dr. J. D. Trobe, W. K. Kellogg Eye Center, 1000 Wall St, Ann Arbor, MI49105.] Drs. Trobe and Butter tested 14 patients with Alzheimer's disease with prominent visual symptoms, 53 controls with normal visual function, and 22 controls with subnormal visual acuity or visual field but no Alzheimer's disease. Their tests were designed to quantitate "integrative visual function." The tests were performed poorly by all patients with Alzheimer's disease but well by all controls. The actual tests given are depicted in the paper, and most would be relatively easy for any ophthalmologist or neurologist to have on hand and use regularly if only a corporate entity could be induced to manufacture such plates as an Alzheimer's disease visual test kit. Lyn A. Sedwick, M.D. Immunoblastic B-Cell Malignant Lymphoma Involving the Orbit and Maxillary Sinus in a Patient with Acquired Immune Deficiency Syndrome. Font RL, Laucirica R, Patrinely JR. Ophthalmology JClin Neuro-ophthalmol, Vol. 13, No.4, 1993 1993;100:966-70 Gun). [Reprint requests to Dr. R. L. Font, Cullen Eye Institute, Baylor College of Medicine, One Baylor Plaza, Houston, TX 77030.] A 44-year-old man with AIDS developed a right orbital and maxillary sinus mass which was removed. Immunohistochemical studies showed B-cell immunoblastic lymphoma with immunophenotypic coexpression of T-cell markers. Clinical, computed tomographic, and immunohistologic pictures are included. Lyn A. Sedwick, M.D. Ocular Fundus Findings in Malawian Children with Cerebral Malaria. Lewallen 5, Taylor TE, Molyneux ME, Wills BA, Courtright P. Ophthalmology 1993;100:857-61 Gun). [Reprint requests to Dr. M. E. Molyneux, FRCP, Liverpool School of Tropical Medicine, Pembroke Place, Liverpool L3 5QA, UK.] The authors examined the ocular fundi of all children admitted to the Malaria Project Ganuary to April 1992; in Blantyre, Malawi, Africa) with cerebral malaria. They found that papilledema and extramacular edema were highly correlated with a poor outcome (death or serious neurologic impairment). Other fundus findings are described, such as hemorrhages and macular edema, and are associated with a more favorable prognosis. Lyn A. Sedwick, M.D. Bilateral Optic Neuropathy as the Initial Manifestation of Systemic Sarcoidosis. DeBroff BM, Donahue SP. Am J Ophthalmol 1993;116:108-11 Gul). [Inquiries to Dr. B. M. DeBroff, University of Pittsburgh Medical Center, 230 Lothrop St., Pittsburgh, PA 15213.] A 28-year-old black lady with sequential visual loss attributed to retrobulbar optic neuritis is described. Her brain magnetic resonance imaging was normal, but laboratory workup showed an increased angiotensin-converting enzyme and erythrocyte sedimentation rate. Computed tomography of the lungs showed hilar adenopathy. Her vision and hilar adenopathy improved on oral corticosteroids, but she refused further testing, such as lung or conjunctival biopsy, for sarcoidosis. As ever, a |