| Title |
The first Jacobson Lecture. Familial idiopathic intracranial hypertension. |
| Creator |
James J. Corbett, MD, University Of Mississippi |
| Affiliation |
Department of Neurology, University of Mississippi Medical Center, Jackson, Mississippi 39216, USA. |
| Abstract |
BACKGROUND: Case reports of familial idiopathic intracranial hypertension (IIH) have appeared sporadically and infrequently. METHODS: We reviewed the medical records of all patients with IIH seen at our institution to identify the number of familial cases. RESULTS: Out of a cohort of 237 patients with IIH, we identified 27 members (25 women and 2 men) from 11 families, with IIH usually self-reported or reported by the index case. In 7 of the 11 families, the relationship was parent to child; in 4, it was sibling. Obesity was present in 85% of the family members. CONCLUSIONS: Familial IIH appears to be more common than reported previously. A systematic evaluation of first-degree relatives may help to identify more cases. A study of the patterns of inheritance and associated co-morbidities may result in better understanding of the genetic issues with this disorder. |
| Subject |
Adolescent; Adult; Cerebrospinal Fluid Pressure; Cohort Studies; Comorbidity; Female; Genetic Predisposition to Disease; Genetic Testing; Headache; Humans; Inheritance; Patterns; Male; Middle Older people; Obesity; Papilledema; Prevalence; Pseudotumor Cerebri; Young Adult |
| Format |
application/pdf |
| Publication Type |
Journal Article |
| Collection |
Neuro-Ophthalmology Virtual Education Library: Journal of Neuro-Ophthalmology Archives: https://novel.utah.edu/jno/ |
| Publisher |
Lippincott, Williams & Wilkins |
| Holding Institution |
Spencer S. Eccles Health Sciences Library, University of Utah |
| Rights Management |
© North American Neuro-Ophthalmology Society |
| Setname |
ehsl_novel_jno |
| ID |
225756 |
| Reference URL |
https://collections.lib.utah.edu/ark:/87278/s6bs1z7n/225756 |
