| Title |
Multifocal electroretinographic abnormalities in ethambutol-induced visual loss. |
| Creator |
Liu, Yao; Dinkin, Marc J; Loewenstein, John I; Joseph F. Rizzo III, M.D.; Cestari, Dean M |
| Affiliation |
Neuro-Ophthalmology Service, Massachusetts Eye and Ear Infirmary, Harvard Medical School, Boston, Massachusetts 02114, USA. |
| Abstract |
Two patients who developed decreased visual acuity after several months of ethambutol treatment for Mycobacterium avium-intracellulare infection had bitemporal visual field defects that suggested optic chiasm damage. Multifocal electroretinography (mfERG) disclosed markedly low-amplitude responses at fixation and in the regions corresponding to the visual field defects. These results suggested that the visual dysfunction might be entirely attributable to retinal rather than optic nerve toxicity. These are the first reported patients to show mfERG abnormalities that correspond to bitemporal visual field defects and add to the growing evidence that ethambutol damages the retina. |
| Subject |
Older people; Antitubercular Agents; Electroretinography; Ethambutol; Female; Humans; Middle Older people; Mycobacterium avium-intracellulare Infection; Pattern Recognition, Visual; Photoreceptor Cells, Vertebrate; Prognosis; Recovery of Function; Retina; Retinal Degeneration; Vision, Low; Visual Fields |
| Format |
application/pdf |
| Publication Type |
Journal Article |
| Collection |
Neuro-Ophthalmology Virtual Education Library: Journal of Neuro-Ophthalmology Archives: https://novel.utah.edu/jno/ |
| Publisher |
Lippincott, Williams & Wilkins |
| Holding Institution |
Spencer S. Eccles Health Sciences Library, University of Utah |
| Rights Management |
© North American Neuro-Ophthalmology Society |
| Setname |
ehsl_novel_jno |
| ID |
225743 |
| Reference URL |
https://collections.lib.utah.edu/ark:/87278/s6bs1z7n/225743 |
