Title |
Late Ipsilateral Recurrence of Oschemic Optic Neuropathy in Giant Cell Arteritis |
Creator |
Kim, N; Trobe, JD; Flint, A; Keoleian, G |
Affiliation |
Departments of Ophthalmology, University of Michigan Medical School, Ann Arbor, Michigan, USA. |
Abstract |
A patient with arteriosclerosis, diabetes mellitus, and giant cell arteritis (GCA) treated continuously with low-dose prednisone developed anterior ischemic optic neuropathy (AION) at 5 and 13 months after clinical diagnosis of GCA. At the time of late recurrent AION, there were no systemic symptoms or elevations in acute phase reactants to signal active arteritis, yet temporal artery biopsy disclosed dramatic inflammation, forcing the presumption that the infarct was arteritic. Recurrent systemic symptoms and elevation of acute phase reactants are not reliable warning signs of reactivated GCA. In patients at high risk for corticosteroid complications, late biopsy may be a reasonable guide to corticosteroid weaning. |
Subject |
Older people; Older people, 80 and over; Anti-Inflammatory Agents/administration & dosage; Drug Administration Schedule; Fundus Oculi; Giant Cell Arteritis/complications; Giant Cell Arteritis/drug therapy; Giant Cell Arteritis/pathology; Humans; Male; Optic Neuropathy, Ischemic/etiology; Optic Neuropathy, Ischemic/pathology; Optic Neuropathy, Ischemic/physiopathology; Optic Neuropathy, Ischemic/prevention & control; Prednisone/administration & dosage; Recurrence/prevention & control; Temporal Arteries/pathology; Treatment Failure; Visual Acuity; Visual Fields |
Format |
application/pdf |
Publication Type |
Journal Article |
Collection |
Neuro-Ophthalmology Virtual Education Library: Journal of Neuro-Ophthalmology Archives: https://novel.utah.edu/jno/ |
Publisher |
Lippincott, Williams & Wilkins |
Holding Institution |
Spencer S. Eccles Health Sciences Library, University of Utah |
Rights Management |
© North American Neuro-Ophthalmology Society |
Setname |
ehsl_novel_jno |
ID |
225152 |
Reference URL |
https://collections.lib.utah.edu/ark:/87278/s63f7vpw/225152 |