| Title |
Transient worsening of optic neuropathy as a sequela of the Jarisch Herxheimer reaction in the treatment of Lyme disease. |
| Creator |
Strominger, MB; Slamovits, TL; Herskovitz, S; Lipton, RB |
| Affiliation |
Department of Ophthalmology, Montefiore Medical Center, Bronx, NY 10467. |
| Abstract |
A 58-year-old woman developed neurologic and neuroophthalmologic manifestations of Lyme disease, including a radiculomyelitis, cranial neuritis and mild right optic neuropathy. Upon treatment with intravenous ceftriaxone a Jarisch-Herxheimer reaction occurred with encephalopathy, mild fever, worsening radiculomyelitis, and deterioration of her visual acuity. Intravenous methylprednisolone was given, and the visual acuity recovered over 72 hours. This case suggests that transient worsening of optic neuropathy can develop as a sequela of the Jarisch-Herxheimer reaction in the treatment of Lyme disease. |
| Subject |
Ceftriaxone/adverse effects; Ceftriaxone/therapeutic use; Encephalomyelitis/etiology; Female; Fever/etiology; Humans; Lyme Disease/complications; Lyme Disease/drug therapy; Methylprednisolone/therapeutic use; Middle Older people; Optic Nerve Diseases/etiology; Optic Nerve Diseases/physiopathology; Radiculopathy/etiology; Visual Acuity/drug effects |
| Format |
application/pdf |
| Publication Type |
Journal Article |
| Collection |
Neuro-Ophthalmology Virtual Education Library: Journal of Neuro-Ophthalmology Archives: https://novel.utah.edu/jno/ |
| Publisher |
Lippincott, Williams & Wilkins |
| Holding Institution |
Spencer S. Eccles Health Sciences Library, University of Utah |
| Rights Management |
© North American Neuro-Ophthalmology Society |
| Setname |
ehsl_novel_jno |
| ID |
224572 |
| Reference URL |
https://collections.lib.utah.edu/ark:/87278/s6qg200m/224572 |
