A novel MRI-based screening method for assessing atrio-esophageal fistula risk following cardia ablation

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Publication Type honors thesis
School or College College of Science
Department Bioengineering
Creator Taggart, Maxwell M.
Title A novel MRI-based screening method for assessing atrio-esophageal fistula risk following cardia ablation
Year graduated 2014
Date 2014-12
Description Atrio-esophageal fistulas affect 1 in 2000 patients who undergo cardiac ablation procedures with a mortality rate of 93%. Methods for detecting atrio-esophageal fistula formation that are objective and non-invasive could reduce the mortality associated with this disease. This study was performed retrospectively on human patients who had received a late gadolinium enhancement MRI (LGE-MRI) within 24 hours of undergoing a cardiac ablation. The study hypothesis was that image enhancement on the anterior esophageal wall following RF cardiac ablation was predictive of a patient's likelihood of developing an atrio-esophageal fistula. Presence of image enhancement on the anterior esophageal wall was compared with patient symptoms and endoscopy findings to determine if the LGE-MRI classification scheme used in the study could predict the risk that a patient would develop an atrio-esophageal fistula. Patients with more than 50% of their anterior esophageal wall showing image enhancement were found to have a higher likelihood of presenting with symptoms consistent with esophageal damage than patients with less than 50% anterior wall coverage. This method should allow physicians to more accurately detect patients who are at risk of developing an atrio-esophageal fistula and to perform therapeutic interventions.
Type Text
Publisher University of Utah
Subject Magnetic resonance imaging; Cardia ablation; Trio-esophageal fistual
Language eng
Rights Management Copyright © Maxwell M. Taggart 2014
Format Medium application/pdf
Format Extent 188,455 bytes
Identifier etd3/id/3630
Permissions Reference URL https://collections.lib.utah.edu/ark:/87278/s6992j2p
ARK ark:/87278/s6nc98hn
Setname ir_htoa
Date Created 2015-07-28
Date Modified 2019-07-09
ID 197182
Reference URL https://collections.lib.utah.edu/ark:/87278/s6nc98hn
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