Parinaud's syndrome with impaired upward saccades and otherwise normal vertical eye movements
abnormal saccades, range of eye movements, abnormal range of eye movements, smooth pursuit, normal VOR, Dorsal midbrain syndrome
Daniel R. Gold, DO, Departments of Neurology, Ophthalmology, Neurosurgery, Otolaryngology - Head & Neck Surgery, Emergency Medicine, and Medicine, The Johns Hopkins School of Medicine
This is a 50-yo-man who suffered a dorsal midbrain stroke. Exam demonstrated normal vertical range of eye movements, normal vertical VOR and smooth pursuit, but inability to perform upward saccades. Another feature of Parinaud's syndrome seen on his exam was light-near dissociation (not shown in this video where he was pharmacologically dilated). Occasionally, a dorsal midbrain syndrome can affect upward saccades with relative sparing of other vertical eye movements, and the patient may have a normal range of vertical movements.
Spencer S. Eccles Health Sciences Library, University of Utah