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Show Development and implementation of a standardized pharmacological approach for neonatal seizure medication in the Newborn Intensive Care Unit Jennica Royce, RN, BSN, DNP-NNP Student May 2017 Anticonvulsant medications have been studied and approved for the treatment of neonatal seizures, none have demonstrated superior efficacy. The fundamental strategy in treating neonatal seizures involves using a standardized approach to control seizure activity effectively. Research supports using standardized, protocol-driven treatments, to improve consistency and patient outcomes. Project Chair: Julieanne Schiefelbein, DNP, NNP, PNP Content Expert: Betsy Ostrander, MD METHODS PURPOSE The purpose of this project was to develop a standardized pharmacological approach to control seizure activity, reducing potential damage to the neonate’s developing brain. BACKGROUND • It is estimated that the overall incidence of neonatal seizures is 1:3 per 1,000 live births in term infants. • A standardized approach to seizure management was developed, based on available research and the clinical expertise of a Pediatric Neurologist. GRAPHIC • An educational PowerPoint was developed and approved by the project committee. • An in-service was presented to neonatal nurse practitioners at local level III and IV NICUs. CONCLUSIONS/IMPLICATIONS • The standardized pharmacological approach was disseminated to local NICUs and an abstract was submitted to a neonatal conference. • Preterm infants have a tenfold increased incidence of seizures. • Positive feedback was received regarding the inservice and questions addressed at the time of presentation. • There is a paucity of evidence identifying the best anticonvulsant for neonatal seizures. • A follow-up survey is recommended to evaluate the effectiveness of the standardized approach. METHODS |