Myelin oligodendrocyte glycoprotein (MOG) - antibody optic neuritis

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Identifier EEC-MOG-NOVEL
Title Myelin oligodendrocyte glycoprotein (MOG) - antibody optic neuritis
Subject Myelin oligodendrocyte glycoprotein (MOG)-antibody; MOG-ab
Creator Bryce Buchowicz, MD, Neuro-ophthalmology Fellow, Department of Ophthalmology, Emory University School of Medicine; Valérie Biousse, MD, Cyrus H. Stoner Professor of Ophthalmology, Professor of Ophthalmology and Neurology, Departments of Ophthalmology and Neurology, Emory University School of Medicine
Description This is an illustrated guide to the clinical diagnosis of myelin oligodendrocyte glycoprotein (MOG)-antibody optic neuritis.; ; Myelin oligodendrocyte glycoprotein (MOG) is a glycoprotein on the surface of myelin and is found exclusively in the central nervous system (CNS). MOG likely mediates a complement cascade which causes an inflammatory demyelinating condition of the CNS. It can occur at any age with median onset in the 4th decade. It can be monophasic or often relapsing. The most common presenting feature is optic neuritis. It is frequently associated with bilateral with optic nerve head edema. MRI will commonly show optic nerve sheath enhancement. MOG optic neuritis has better visual outcomes than neuromyelitis optica (NMO), although relapses may be more frequent. MOG commonly causes myelitis or acute disseminated encephalomyelitis (ADEM) in children.
Publisher Spencer S. Eccles Health Sciences Library, University of Utah
Date 2020-06
Type Text; Image
Format application/pdf
Rights Management Copyright 2020. For further information regarding the rights to this collection, please visit:
Collection Neuro-ophthalmology Virtual Education Library: NOVEL
Language eng
ARK ark:/87278/s6fn6q76
Setname ehsl_novel_eec
Date Created 2020-06-10
Date Modified 2020-06-10
ID 1571530
Reference URL
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