Efficacy and Safety of Satralizumab from Two Phase 3 Trials in Neuromyelitis Optica Spectrum Disorder (PDF)

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Identifier 20200309_nanos_sciplatform1_03-pdf
Title Efficacy and Safety of Satralizumab from Two Phase 3 Trials in Neuromyelitis Optica Spectrum Disorder (PDF)
Creator Benjamin Frishberg, Jerome de Seze, Brian Weinshenker, Yusuke Terada, Yuichi Kawata, Athos Gianella-Borradori, H. Christianvon Büdingen, Gaelle Klingelschmitt, Anthony Traboulsee, Takashi Yamamura
Subject Optic Neuritis, Neuro-ophth & Systemic Disease (eg. MS, MG, Thyroid), Optic Nerve Trauma and Treatment, Non-Organic Visual Disorders, Miscellaneous
Description Satralizumab is a humanized recycling monoclonal antibody that binds to the interleukin-6 (IL-6) receptor; IL-6 has been implicated in the pathophysiology of neuromyelitis optica spectrum disorder (NMOSD). Satralizumab was evaluated in patients with NMOSD in two Phase 3 studies: SAkuraSky (NCT02028884) and SAkuraStar (NCT02073279). In this analysis, we assessed the efficacy and safety of satralizumab in the individual study and pooled patient populations, including the subgroup of patients who were seropositive foraquaporin-4 immunoglobulin G (AQP4-IgG).
Relation is Part of NANOS Annual Meeting 2020: Scientific Platform Session I
Contributor Primary Benjamin M. Frishberg, MD
Contributor Secondary Jerome de Seze, Brian Weinshenker, Yusuke Terada, Yuichi Kawata, Athos Gianella-Borradori, H. Christianvon Büdingen, Gaelle Klingelschmitt, Anthony Traboulsee, Takashi Yamamura
Publisher Spencer S. Eccles Health Sciences Library, University of Utah
Date 2020-03
Format application/pdf
Source 2020 North American Neuro-Ophthalmology Society Annual Meeting
Rights Management Copyright 2020. For further information regarding the rights to this collection, please visit: https://NOVEL.utah.edu/about/copyright
Holding Institution North American Neuro-Ophthalmology Association. NANOS Executive Office 5841 Cedar Lake Road, Suite 204, Minneapolis, MN 55416
Collection Neuro-ophthalmology Virtual Education Library: NOVEL http://NOVEL.utah.edu
Language eng
ARK ark:/87278/s6nw4tv1
Setname ehsl_novel_nam
Date Created 2020-04-22
Date Modified 2021-05-06
ID 1543325
Reference URL https://collections.lib.utah.edu/ark:/87278/s6nw4tv1
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