| Identifier |
20200309_nanos_sciplatform1_03-pdf |
| Title |
Efficacy and Safety of Satralizumab from Two Phase 3 Trials in Neuromyelitis Optica Spectrum Disorder (PDF) |
| Creator |
Benjamin Frishberg; Jerome de Seze; Brian Weinshenker; Yusuke Terada; Yuichi Kawata; Athos Gianella-Borradori; H. Christian von Büdingen; Gaelle Klingelschmitt; Anthony Traboulsee; Takashi Yamamura |
| Affiliation |
(BF) The Neurology Center of Southern California, Carlsbad, California; (JS) Department of Neurology, Hôpital de Hautepierre, Paris, France; (BW) Mayo Clinic, Rochester, Minnesota; (YT) (YK) Chugai Pharmaceutical Co., Ltd, Tokyo, Japan; (AG) Chugai Pharma USA, Inc. At the time of the study, Berkeley Heights, New Jersey, Switzerland; (HC) F. Hoffmann-La Roche Ltd,, Basel, Switzerland; (AT) The University of British Columbia, Vancouver, Canada; (TY) National Institute of Neuroscience, National Center of Neurology and Psychiatry, Tokyo, Japan |
| Subject |
Optic Neuritis; Neuro-ophthalmology & Systemic Disease (eg. MS, MG, Thyroid); Optic Nerve Trauma and Treatment; Non-Organic Visual Disorders; Miscellaneous |
| Description |
Satralizumab is a humanized recycling monoclonal antibody that binds to the interleukin-6 (IL-6) receptor; IL-6 has been implicated in the pathophysiology of neuromyelitis optica spectrum disorder (NMOSD). Satralizumab was evaluated in patients with NMOSD in two Phase 3 studies: SAkuraSky (NCT02028884) and SAkuraStar (NCT02073279). In this analysis, we assessed the efficacy and safety of satralizumab in the individual study and pooled patient populations, including the subgroup of patients who were seropositive foraquaporin-4 immunoglobulin G (AQP4-IgG). |
| Date |
2020-03 |
| Language |
eng |
| Format |
application/pdf |
| Type |
Text |
| Source |
2020 North American Neuro-Ophthalmology Society Annual Meeting |
| Relation is Part of |
NANOS Annual Meeting 2020: Scientific Platform Session I |
| Collection |
Neuro-Ophthalmology Virtual Education Library: NANOS Annual Meeting Collection: https://novel.utah.edu/collection/nanos-annual-meeting-collection/ |
| Publisher |
North American Neuro-Ophthalmology Society |
| Holding Institution |
Spencer S. Eccles Health Sciences Library, University of Utah |
| Rights Management |
Copyright 2020. For further information regarding the rights to this collection, please visit: https://NOVEL.utah.edu/about/copyright |
| ARK |
ark:/87278/s6nw4tv1 |
| Setname |
ehsl_novel_nam |
| ID |
1543325 |
| Reference URL |
https://collections.lib.utah.edu/ark:/87278/s6nw4tv1 |
