Monocular horizontal pendular nystagmus in MS

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Identifier Monocular_horizontal_pendular_nystagmus_in_MS
Title Monocular horizontal pendular nystagmus in MS
Subject Pendular Nystagmus
Creator Daniel R. Gold, DO, Departments of Neurology, Ophthalmology, Neurosurgery, Otolaryngology - Head & Neck Surgery, Emergency Medicine, and Medicine, The Johns Hopkins School of Medicine
Description Both of these patients have MS and monocular (OS) horizontal pendular nystagmus. The first patient seen in the video has normal afferent function and no evidence of optic nerve disease in either eye, while the second patient has severe OS>>OD optic nerve disease related to bouts of optic neuritis (there was also a slight torsional pendular nystagmus component). Because pendular nystagmus is commonly seen in MS patients, it has been suggested that the nystagmus might result from a prolonged response time for visual processing, supported by the fact that nystagmus is commonly more intense in the eye with poorer vision. However, pendular nystagmus doesn't change with visual feedback removed, and inducing visual delays by itself is not capable of causing the oscillations seen in MS. Therefore, it's likely that instability in the neural integrator (gaze holding machinery) also plays a significant role in many cases. Explanations for monocular pendular nystagmus in these patients includes 1) ipsilateral afferent dysfunction or 2) perhaps within the unstable neural integrator, certain monocular-projecting cell populations are preferentially damaged.
Publisher Spencer S. Eccles Health Sciences Library, University of Utah
Date 2017
Type Image/MovingImage
Format video/mp4
Rights Management Copyright 2017. For further information regarding the rights to this collection, please visit:
Holding Institution Spencer S. Eccles Health Sciences Library, University of Utah, 10 N 1900 E, SLC, UT 84112-5890
Collection Neuro-ophthalmology Virtual Education Library: NOVEL
Language eng
ARK ark:/87278/s6q852cf
Setname ehsl_novel_gold
Date Created 2017-02-23
Date Modified 2017-08-11
ID 1209724
Reference URL
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