Nystagmus due to paraneoplastic (anti-Yo) brainstem and cerebellar degeneration

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Identifier Anti_Yo
Title Nystagmus due to paraneoplastic (anti-Yo) brainstem and cerebellar degeneration
Subject Abnormal Saccades, Abnormal VORS, Cerebellar, Jerk Nystagmus, Upbeat Nystagmus, Gaze Evoked Nystagmus,
Creator Daniel R. Gold, DO, Departments of Neurology, Ophthalmology, Neurosurgery, Otolaryngology - Head & Neck Surgery, Emergency Medicine, and Medicine, The Johns Hopkins School of Medicine
Description This is a 40-yo-woman with anti-Yo antibody associated with ovarian cancer. Initial symptoms 2.5 years prior (to this video) included imbalance and dysarthria. She complained of oscillopsia which was due to her upbeat nystagmus (presumably the result of brainstem involvement), and diplopia (she had an esotropia greater at distance which is common with cerebellar pathology). There were also intermittent spontaneous saccadic intrusions, hypermetric saccades, choppy smooth pursuit and VOR suppression - ocular motor abnormalities that are commonly seen with posterior fossa disease. At the time when the video was taken (2.5 years after symptom onset), severe brainstem and cerebellar atrophy was apparent on MRI.
Publisher Spencer S. Eccles Health Sciences Library, University of Utah
Date 2017
Type Image/MovingImage
Format video/mp4
Rights Management Copyright 2017. For further information regarding the rights to this collection, please visit: https://NOVEL.utah.edu/about/copyright
Holding Institution Spencer S. Eccles Health Sciences Library, University of Utah, 10 N 1900 E, SLC, UT 84112-5890
Collection Neuro-ophthalmology Virtual Education Library: NOVEL http://NOVEL.utah.edu
Language eng
ARK ark:/87278/s6bz9v92
Setname ehsl_novel_gold
Date Created 2017-02-23
Date Modified 2018-06-11
ID 1209719
Reference URL https://collections.lib.utah.edu/ark:/87278/s6bz9v92
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