| Publication Type |
pre-print |
| School or College |
College of Science |
| Department |
Chemistry |
| Creator |
Poulter, Charles Dale |
| Other Author |
Tian, Box-Xue; Wallrapp, Frank H.; Holiday, Gemma L.; Chow, Jeng-Yeong; Babbitt, Patricia C.; Jacobson, Matthew P. |
| Title |
Predicting the functions and specificity of triterpenoid synthases: a mechanism-based multi-intermediate docking approach |
| Date |
2014-01-01 |
| Description |
Terpenoid synthases construct the carbon skeletons of tens of thousands of natural products. To predict functions and specificity of triterpenoid synthases, a mechanism-based, multi-intermediate docking approach is proposed. In addition to enzyme function prediction, other potential applications of the current approach, such as enzyme mechanistic studies and enzyme redesign by mutagenesis, are discussed. |
| Type |
Text |
| Publisher |
Public Library of Science (PLoS) |
| Volume |
10 |
| Issue |
10 |
| First Page |
1 |
| Last Page |
16 |
| Language |
eng |
| Bibliographic Citation |
Tian, B.-X., Wallrapp, F. H., Holiday, G. L., Chow, J.-Y., Babbitt, P. C., Poulter, C. D., & Jacobson, M. P. (2014). Predicting the functions and specificity of triterpenoid synthases: a mechanism-based multi-intermediate docking approach. PLoS Computational Biology, 10(10), 1-16. |
| Rights Management |
© Charles Dale Poulter |
| Format Medium |
application/pdf |
| Format Extent |
4,505,749 bytes |
| Identifier |
uspace,19055 |
| ARK |
ark:/87278/s69p69r2 |
| Setname |
ir_uspace |
| ID |
712732 |
| Reference URL |
https://collections.lib.utah.edu/ark:/87278/s69p69r2 |
