| Title | Keratin 7 staining in squamous metaplasia of the epithelium of a bronchiolus (human, adult) |
| Creator | Poels, Lambert G. |
| Contributor | Lambert G. Poels, PhD, UMC St Radboud Nijmegen; Paul H. K. Jap, PhD, UMC St Radboud Nijmegen |
| Date | 2006-09-28 |
| Subject | Bronchiolus; Squamous metaplasia; Immunoperoxidase; Immuno-reaction |
| Description | Stain: anti-keratin 7 antibody (Pan-Ck 7) immunoperoxidase staining (with aminoethylcarbazole (AEC) substrate). A red-brown staining with AEC indicates a positive reaction for cytokeratin 7. Note that the top layer only is stained positively for keratin 7 (↓). Upon squamous metaplasia the bronchiolar epithelial cells reduce keratin 7 expression and hence this cytokeratin appears a suitable marker in the study of early metaplastic processes in epithelia e.g., the bronchial tree. |
| Subtype | Image |
| Format | image/jpeg |
| Rights | http://creativecommons.org/licenses/by-nc-nd/2.5/ |
| Collection | Poja Histology Collection - Respiratory System Subset |
| ARK | ark:/87278/s62g0qq2 |
| Setname | ehsl_heal |
| ID | 890766 |
| Reference URL | https://collections.lib.utah.edu/ark:/87278/s62g0qq2 |