Title |
Keratin 7 staining in squamous metaplasia of the epithelium of a bronchiolus (human, adult) |
Creator |
Poels, Lambert G. |
Contributor |
Lambert G. Poels, PhD, UMC St Radboud Nijmegen; Paul H. K. Jap, PhD, UMC St Radboud Nijmegen |
Date |
2006-09-28 |
Subject |
Bronchiolus; Squamous metaplasia; Immunoperoxidase; Immuno-reaction |
Description |
Stain: anti-keratin 7 antibody (Pan-Ck 7) immunoperoxidase staining (with aminoethylcarbazole (AEC) substrate). A red-brown staining with AEC indicates a positive reaction for cytokeratin 7. Note that the top layer only is stained positively for keratin 7 (↓). Upon squamous metaplasia the bronchiolar epithelial cells reduce keratin 7 expression and hence this cytokeratin appears a suitable marker in the study of early metaplastic processes in epithelia e.g., the bronchial tree. |
Subtype |
Image |
Format |
image/jpeg |
Rights |
http://creativecommons.org/licenses/by-nc-nd/2.5/ |
Collection |
Poja Histology Collection - Respiratory System Subset |
ARK |
ark:/87278/s62g0qq2 |
Setname |
ehsl_heal |
ID |
890766 |
Reference URL |
https://collections.lib.utah.edu/ark:/87278/s62g0qq2 |