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Multifocal electroretinographic abnormalities in ethambutol-induced visual loss.

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Title Journal of Neuro-Ophthalmology, December 2008, Volume 28, Issue 4
Date 2008-12
Language eng
Format application/pdf
Type Text
Publication Type Journal Article
Collection Neuro-Ophthalmology Virtual Education Library: Journal of Neuro-Ophthalmology Archives: https://novel.utah.edu/jno/
Publisher Lippincott, Williams & Wilkins
Holding Institution Spencer S. Eccles Health Sciences Library, University of Utah
Rights Management © North American Neuro-Ophthalmology Society
ARK ark:/87278/s6bs1z7n
Setname ehsl_novel_jno
ID 225764
Reference URL https://collections.lib.utah.edu/ark:/87278/s6bs1z7n

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Title Multifocal electroretinographic abnormalities in ethambutol-induced visual loss.
Creator Liu, Yao; Dinkin, Marc J; Loewenstein, John I; Joseph F. Rizzo III, M.D.; Cestari, Dean M
Affiliation Neuro-Ophthalmology Service, Massachusetts Eye and Ear Infirmary, Harvard Medical School, Boston, Massachusetts 02114, USA.
Abstract Two patients who developed decreased visual acuity after several months of ethambutol treatment for Mycobacterium avium-intracellulare infection had bitemporal visual field defects that suggested optic chiasm damage. Multifocal electroretinography (mfERG) disclosed markedly low-amplitude responses at fixation and in the regions corresponding to the visual field defects. These results suggested that the visual dysfunction might be entirely attributable to retinal rather than optic nerve toxicity. These are the first reported patients to show mfERG abnormalities that correspond to bitemporal visual field defects and add to the growing evidence that ethambutol damages the retina.
Subject Older people; Antitubercular Agents; Electroretinography; Ethambutol; Female; Humans; Middle Older people; Mycobacterium avium-intracellulare Infection; Pattern Recognition, Visual; Photoreceptor Cells, Vertebrate; Prognosis; Recovery of Function; Retina; Retinal Degeneration; Vision, Low; Visual Fields
OCR Text Show
Format application/pdf
Publication Type Journal Article
Collection Neuro-Ophthalmology Virtual Education Library: Journal of Neuro-Ophthalmology Archives: https://novel.utah.edu/jno/
Publisher Lippincott, Williams & Wilkins
Holding Institution Spencer S. Eccles Health Sciences Library, University of Utah
Rights Management © North American Neuro-Ophthalmology Society
Setname ehsl_novel_jno
ID 225743
Reference URL https://collections.lib.utah.edu/ark:/87278/s6bs1z7n/225743
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