Publication Type |
Journal Article |
School or College |
College of Science |
Department |
Biology |
Creator |
Olivera, Baldomero M.; Bulaj, Grzegorz |
Other Author |
Teichert, Russell W.; Jimenez, Elsie C.; Twede, Vernon; Watkins, Maren; Hollmann, Michael |
Title |
Novel conantokins from Conus parius venom are specific antagonists of N-methyl-D-aspartate receptors |
Date |
2007 |
Description |
We report the discovery and characterization of three conantokin peptides from the venom of Conus parius. Each peptide (conantokin-Pr1, -Pr2, and -Pr3) contains 19 amino acids with three γ-carboxyglutamate (Gla) residues, a post-translationally modified amino acid characteristic of conantokins. The new peptides contain several amino acid residues that differ from previous conantokin consensus sequences. |
Type |
Text |
Publisher |
American Society for Biochemistry and Molecular Biology (ASBMB) |
Volume |
282 |
Issue |
51 |
First Page |
36905 |
Last Page |
36913 |
Subject |
Conotoxins; Conantokins; Conus parius; Antagonists; n-methyl-D-aspartate receptors |
Subject LCSH |
Conus; Marine toxins |
Dissertation Institution |
University of Utah |
Language |
eng |
Bibliographic Citation |
Teichert, R. W., Jimenez, E. C., Twede, V., Watkins, M., Hollmann, M., Bulaj, G., & Olivera, B. M. (2007). Novel conantokins from Conus parius venom are specific antagonists of N-Methyl-D-aspartate receptors. Journal of Biological Chemistry, 282(51), 36905-13. |
Rights Management |
(c)American Society for Biochemistry and Molecular Biology (ASBMB) http://www.asbmb.org/ |
Format Medium |
application/pdf |
Format Extent |
740,059 bytes |
Identifier |
ir-main,8488 |
ARK |
ark:/87278/s6zs3dvf |
Setname |
ir_uspace |
ID |
704784 |
Reference URL |
https://collections.lib.utah.edu/ark:/87278/s6zs3dvf |