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The Bascom Palmer Eye Institute Lyme/syphilis survey.

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Title Journal of Neuro-Ophthalmology, December 1990, Volume 10, Issue 4
Date 1990-12
Language eng
Format application/pdf
Type Text
Publication Type Journal Article
Collection Neuro-Ophthalmology Virtual Education Library: Journal of Neuro-Ophthalmology Archives: https://novel.utah.edu/jno/
Publisher Lippincott, Williams & Wilkins
Holding Institution Spencer S. Eccles Health Sciences Library, University of Utah
Rights Management © North American Neuro-Ophthalmology Society
ARK ark:/87278/s6n3330t
Setname ehsl_novel_jno
ID 226244
Reference URL https://collections.lib.utah.edu/ark:/87278/s6n3330t

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Title The Bascom Palmer Eye Institute Lyme/syphilis survey.
Creator Smith, J.L.; Crumpton, B.C.; Hummer, J.
Affiliation Bascom Palmer Eye Institute, Department of Ophthalmology, University of Miami School of Medicine, Florida.
Abstract Serologic screening of patients for Lyme borreliosis began at the Bascom Palmer Eye Institute (BPEI) in September 1987. This report reviews the data on 641 sera from that date up to January 1, 1990. Initially only immunofluorescent (IFA) IgG and IgM titers were obtained. Because of increasing numbers of borderline and positive IFA tests, a Lyme enzyme linked immunosorbent assay (ELISA) was added in April 1988. Also, because of significant serologic cross reactivity in patients exposed to Treponema pallidum, rapid plasma reagin (RPR) and fluorescent treponemal antibody absorption (FTA-ABS) tests were added to the serologic screening panel. Of all sera tested, 10% showed reactive RPR tests and 22% showed reactive FTA-ABS tests. Lyme IFA IgG titers were greater than or equal to 1:64 in 17% of the sera, and Lyme ELISA tests were greater than 1.25 in 15% of the sera. Our experience agrees with reports that serum RPR or VDRL tests are nonreactive in Lyme borreliosis, and that false positive FTA-ABS tests can occur in Lyme borreliosis. The importance of getting all four tests--RPR, FTA-ABS, Lyme IFA IgG and IgM, and Lyme ELISA--in all patients suspected of spirochetal disease is emphasized.
Subject Adolescent; Adult; Older people; Antibodies, Bacterial; Borrelia burgdorferi Group; Child; Cross Reactions; Enzyme-Linked Immunosorbent Assay; Female; Florida; Fluorescent Antibody Technique; Humans; Lyme Disease; Male; Mass Screening; Middle Older people; Pilot Projects; Predictive Value of Tests; Syphilis; Syphilis Serodiagnosis; Treponema pallidum
OCR Text Show
Format application/pdf
Publication Type Journal Article
Collection Neuro-Ophthalmology Virtual Education Library: Journal of Neuro-Ophthalmology Archives: https://novel.utah.edu/jno/
Publisher Lippincott, Williams & Wilkins
Holding Institution Spencer S. Eccles Health Sciences Library, University of Utah
Rights Management © North American Neuro-Ophthalmology Society
Setname ehsl_novel_jno
ID 226221
Reference URL https://collections.lib.utah.edu/ark:/87278/s6n3330t/226221
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