Miller Fisher Syndrome - Ophthalmoplegia, Ptosis and Ataxia
Alternative Title
Video 2.7 The triad of Miller Fisher syndrome from Neuro-Ophthalmology and Neuro-Otology Textbook
Creator
Daniel R. Gold, DO
Affiliation
(DRG) Departments of Neurology, Ophthalmology, Neurosurgery, Otolaryngology - Head & Neck Surgery, Emergency Medicine, and Medicine, The Johns Hopkins School of Medicine, Baltimore, Maryland
Subject
Range of Eye Movements/Motility Abnormal; Miller Fisher Syndrome
Description
𝗢𝗿𝗶𝗴𝗶𝗻𝗮𝗹 𝗗𝗲𝘀𝗰𝗿𝗶𝗽𝘁𝗶𝗼𝗻: This is a young man who presented with ptosis, difficulty moving the eyes and gait imbalance several weeks after a GI illness. Miller Fisher syndrome was diagnosed, IVIG therapy was initiated, and anti-Gq1b antibodies came back extremely elevated. In addition to ophthalmoplegia, and ataxia, hyporeflexia was also present. 𝗡𝗲𝘂𝗿𝗼-𝗼𝗽𝗵𝘁𝗵𝗮𝗹𝗺𝗼𝗹𝗼𝗴𝘆 𝗮𝗻𝗱 𝗡𝗲𝘂𝗿𝗼-𝗼𝘁𝗼𝗹𝗼𝗴𝘆 𝗧𝗲𝘅𝘁𝗯𝗼𝗼𝗸 𝗟𝗲𝗴𝗲𝗻𝗱: This is a young man who presented with ptosis, ophthalmoplegia and gait imbalance several weeks after a GI illness. MFS was diagnosed, IVIG therapy was initiated, and anti-Gq1b antibodies came back extremely elevated. The typical triad of MFS includes ophthalmoplegia, ataxia, and hyporefexia which were all present in this case. https:// collections.lib.utah.edu/ark:/87278/s66m6w3z