Identifier |
walsh_2013_s2_c4 |
Title |
Is it Naughty or Nice? |
Creator |
Daniel Gold, Madhura A. Tamhankar, Laura J. Balcer, MD, Professor, Department of Neurology, NYU Langone; Thomas Coyne, Clyde E. Markowitz, Steven L. Galetta, MD, NYU Langone |
Subject |
Anterior optic neuritis; Ring-enhancing lesions; Fulminant MS |
History |
Subjective fever and cold symptoms were noted 3 weeks prior, and she had experienced transient visual obscurations for 2 weeks. |
Pathology |
Neuropathology showed vast areas of confluent demyelination, marked histiocytic infiltrates, perivascular lymphocytic cuffs, and numerous Creutzfeldt cells - suggestive of acute fulminant MS (Marburg variant), neuropathology did not show multifocal inflammation and demyelination centered around venous structures, which would be expected in ADEM. |
Disease/Diagnosis |
Acute fulminant MS (Marburg disease) |
Clinical |
Visual acuity was 20/400 OD and CF at 1 foot OS with dyschromatopsia, left RAPD and bilateral severe optic disc swelling with hemorrhages; large multifocal ringenhancinglesions with surrounding vasogenic edema centered around the gray-white junction, and bilateral opticnerve enhancement. |
Presenting Symptom |
A 19-year-old woman presented with 4 days of rapidly progressive vision loss in both eyes associated with pain on eye movements. |
Neuroimaging |
CT Scan; MRI |
Date |
2013-02-10 |
References |
Attached |
Language |
eng |
Format |
application/pdf |
Type |
Text |
Source |
45th Annual Frank Walsh Society Meeting |
Relation is Part of |
Case presented at the NANOS 2013 Walsh Session, February 10 |
Collection |
Neuro-ophthalmology Virtual Education Library: NOVEL http://NOVEL.utah.edu |
Publisher |
Spencer S. Eccles Health Sciences Library, University of Utah |
Holding Institution |
North American Neuro-Ophthalmology Association (NANOS), Copyright 2013. For further information regarding the rights to this collection, please visit http://library.med.utah.edu/NOVEL |
ARK |
ark:/87278/s66m64dw |
Contributor Primary |
Kedar, Sachin |
Contributor Secondary |
Rucker, Janet C |
Setname |
ehsl_novel_fbw |
ID |
179165 |
Reference URL |
https://collections.lib.utah.edu/ark:/87278/s66m64dw |