Is it Naughty or Nice?

Update item information
Identifier walsh_2013_s2_c4
Title Is it Naughty or Nice?
Creator Gold, Daniel; Tamhankar, Madhura A; Laura J. Balcer, MD, Professor, Department of Neurology, NYU Langone; Coyne, Thomas; Markowitz, Clyde E; Steven L. Galetta, MD, NYU Langone
Subject Anterior optic neuritis; Ring-enhancing lesions; Fulminant MS
Presenting Symptom A 19-year-old woman presented with 4 days of rapidly progressive vision loss in both eyes associated with pain on eye movements.
History Subjective fever and cold symptoms were noted 3 weeks prior, and she had experienced transient visual obscurations for 2 weeks.
Clinical Visual acuity was 20/400 OD and CF at 1 foot OS with dyschromatopsia, left RAPD and bilateral severe optic disc swelling with hemorrhages; large multifocal ringenhancinglesions with surrounding vasogenic edema centered around the gray-white junction, and bilateral opticnerve enhancement.
Neuroimaging CT Scan; MRI
Pathology Neuropathology showed vast areas of confluent demyelination, marked histiocytic infiltrates, perivascular lymphocytic cuffs, and numerous Creutzfeldt cells - suggestive of acute fulminant MS (Marburg variant), neuropathology did not show multifocal inflammation and demyelination centered around venous structures, which would be expected in ADEM.
Disease/Diagnosis Acute fulminant MS (Marburg disease)
References Attached
Relation is Part of Case presented at the NANOS 2013 Walsh Session, February 10
Contributor Primary Kedar, Sachin
Contributor Secondary Rucker, Janet C
Publisher Spencer S. Eccles Health Sciences Library, University of Utah
Date 2013-02-10
Type Text
Format application/pdf
Source 45th Annual Frank Walsh Society Meeting
Holding Institution North American Neuro-Ophthalmology Association (NANOS), Copyright 2013. For further information regarding the rights to this collection, please visit http://library.med.utah.edu/NOVEL
Collection Neuro-ophthalmology Virtual Education Library: NOVEL http://NOVEL.utah.edu
Language eng
ARK ark:/87278/s66m64dw
Setname ehsl_novel_fbw
Date Created 2013-12-12
Date Modified 2021-05-06
ID 179165
Reference URL https://collections.lib.utah.edu/ark:/87278/s66m64dw