Patient-specific instrumentation in total knee arthroplasty provides no improvement in component alignment

Improved component alignment in TKA remains a commonly cited benefit of MRI based patient-specific instrumentation (PSI). We hypothesized that PSI would lead to improved alignment versus traditional instrumentation (TI) during primary TKA. Fifty-eight knees (54 patients) that underwent TKA with PSI were compared to 62 knees that had previously undergone TKA with TI. Radiographs were evaluated for mechanical axis and alignment of the femoral and tibial components. Alignment was similar between the groups. However, the PSI group showed fewer knees in the target range for posterior tibial slope (PSI 38% vs. TI 61%, p=0.01) in addition to a trend for fewer knees in target for femoral flexion (PSI 40% vs. TI 56%, p=0.07). This study demonstrated no improvement in overall alignment and perhaps a worsening of the tibial slope.