Identifier |
20210221_nanos_journalclub1_07-abstract |
Title |
Effect of Prostaglandin Analogs on Cerebrospinal Fluid Reabsorption Via Nasal Mucosa |
Creator |
Prem S. Subramanian, Michelle G. Pedler, J. Mark Petrash |
Affiliation |
(PSS) (MGP) (JMP) Sue Anschutz-Rodgers UCHealth Eye Center/University of Colorado School of Medicine, Aurora, CO |
Subject |
High Intracranial Pressure/Headache; Pseudotumor Cerebri |
Description |
Cerebrospinal fluid (CSF) outflow has been demonstrated along nasal lymphatics via olfactory nerve projections; flow may be increased by stimulating lymphatic contractility using agents such as noradrenaline and the thromboxane A2 analog U46619. Lymphatics elsewhere in the body show increased contractility upon exposure to the prostaglandin F2alpha analog isoprostane-8- epi-prostaglandin. We investigated the ability of ophthalmic prostaglandin F2alpha analogs to increase CSF outflow when applied to the nasal mucosa by inhalation. |
Date |
2021-02 |
Language |
eng |
Format |
application/pdf |
Type |
Text |
Source |
2021 North American Neuro-Ophthalmology Society Annual Meeting |
Relation is Part of |
NANOS Annual Meeting 2021: Journal Club: What You Need to Know Now! |
Collection |
Neuro-Ophthalmology Virtual Education Library: NANOS Annual Meeting Collection: https://novel.utah.edu/collection/nanos-annual-meeting-collection/ |
Publisher |
North American Neuro-Ophthalmology Society |
Holding Institution |
Spencer S. Eccles Health Sciences Library, University of Utah |
Rights Management |
Copyright 2021. For further information regarding the rights to this collection, please visit: https://NOVEL.utah.edu/about/copyright |
ARK |
ark:/87278/s6ns6ssf |
Setname |
ehsl_novel_nam |
ID |
1694264 |
Reference URL |
https://collections.lib.utah.edu/ark:/87278/s6ns6ssf |