Publication Type |
Journal Article |
School or College |
College of Science |
Department |
Physics |
Creator |
Gerton, Jordan |
Other Author |
Xie, Changan; Mu, Chun; Cox, Jonathan R. |
Title |
Tip-enhanced fluorescence microscopy of high-density samples |
Date |
2006 |
Description |
High-density samples of fluorescent quantum dots (QDs) were imaged using an apertureless near-field optical microscopy technique. QD fluorescence was modulated by oscillating a silicon atomic force microscope tip above an illuminated sample and a lock-in amplifier was used to suppress background from the excitation laser. Spatial resolution near 10 nm and a peak signal-to-noise ratio (SNR) of ~60 were achieved. Individual QDs within high-density ensembles were still easily resolved (SNR>5) at a density of 14 QDs/µm2. These results have favorable implications for the eventual nanoscale imaging of viable biological systems, such as cellular membranes. |
Type |
Text |
Publisher |
American Institute of Physics (AIP) |
Journal Title |
Applied Physics Letters |
Volume |
89 |
Issue |
14 |
First Page |
143117 |
DOI |
10.1063/1.2358122 |
citatation_issn |
36951 |
Language |
eng |
Bibliographic Citation |
Xie, C., Mu, C., Cox, J. R., & Gerton, J. M. (2006). Tip-enhanced fluorescence microscopy of high-density samples. Applied Physics Letters, 89(14), 143117. |
Rights Management |
(c)American Institute of Physics. The following article by Xie, C., Mu, C., Cox, J. R., & Gerton, J. M. appeared in Applied Physics Letters, 89(14) 2006 and may be found at (10.1063/1.2358122). |
Format Medium |
application/pdf |
Format Extent |
281,631 bytes |
Identifier |
ir-main,11286 |
ARK |
ark:/87278/s6s18m48 |
Setname |
ir_uspace |
ID |
707125 |
Reference URL |
https://collections.lib.utah.edu/ark:/87278/s6s18m48 |