Publication Type |
pre-print |
School or College |
College of Science |
Department |
Chemistry |
Creator |
Poulter, Charles Dale |
Other Author |
Tian, Box-Xue; Wallrapp, Frank H.; Holiday, Gemma L.; Chow, Jeng-Yeong; Babbitt, Patricia C.; Jacobson, Matthew P. |
Title |
Predicting the functions and specificity of triterpenoid synthases: a mechanism-based multi-intermediate docking approach |
Date |
2014-01-01 |
Description |
Terpenoid synthases construct the carbon skeletons of tens of thousands of natural products. To predict functions and specificity of triterpenoid synthases, a mechanism-based, multi-intermediate docking approach is proposed. In addition to enzyme function prediction, other potential applications of the current approach, such as enzyme mechanistic studies and enzyme redesign by mutagenesis, are discussed. |
Type |
Text |
Publisher |
Public Library of Science (PLoS) |
Volume |
10 |
Issue |
10 |
First Page |
1 |
Last Page |
16 |
Language |
eng |
Bibliographic Citation |
Tian, B.-X., Wallrapp, F. H., Holiday, G. L., Chow, J.-Y., Babbitt, P. C., Poulter, C. D., & Jacobson, M. P. (2014). Predicting the functions and specificity of triterpenoid synthases: a mechanism-based multi-intermediate docking approach. PLoS Computational Biology, 10(10), 1-16. |
Rights Management |
(c) Charles Dale Poulter |
Format Medium |
application/pdf |
Format Extent |
4,505,749 bytes |
Identifier |
uspace,19055 |
ARK |
ark:/87278/s69p69r2 |
Setname |
ir_uspace |
ID |
712732 |
Reference URL |
https://collections.lib.utah.edu/ark:/87278/s69p69r2 |