Development of a novel, coumarin-europium sensor for reactive oxidizing species

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Publication Type honors thesis
School or College College of Science
Department Chemistry
Faculty Mentor Amy M. Barrios
Creator Sanders, Sara
Title Development of a novel, coumarin-europium sensor for reactive oxidizing species
Year graduated 2012
Date 2012-05
Description The synthetic framework has been developed for two fluorescent probes of Reactive Oxidizing Species (RoxS) based on a coumarin-europium fluorescence pair. The coumarin moiety's selectivity for hydrogen peroxide coupled with 620 nm shifted emission of the europium will make these novel sensors biologically useful imaging tools. The two probe compounds, L1 and L2, are based on known Europium Chelators and were easily synthesized from small molecule building blocks in good yield.
Type Text
Publisher University of Utah
Subject Reactive Oxygen Species - analysis
Language eng
Rights Management (c) Sara Sanders
Format Medium application/pdf
Format Extent 911,980 bytes
Permissions Reference URL https://collections.lib.utah.edu/details?id=1306568
ARK ark:/87278/s6k10dj8
Setname ir_htoa
ID 205807
Reference URL https://collections.lib.utah.edu/ark:/87278/s6k10dj8
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