New family of Conus peptides targeted to the nicotinic acetylcholine receptor

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Publication Type Journal Article
School or College College of Science
Department Biology
Creator Olivera, Baldomero M.; Gray, William Robert
Other Author Hopkins, Chris; Grilley, Michelle; Miller, Charleen; Shon, Ki-Joon; Cruz, Lourdes J.; Dykert, John; Rivier, Jean; Yoshikami, Doju
Title New family of Conus peptides targeted to the nicotinic acetylcholine receptor
Date 1995
Description In this work, a new family of Conus peptides, the αA-conotoxins, which target the nicotinic acetylcholine receptor, is defined. The first members of this family have been characterized from the eastern Pacific species, Conus purpurascens (the purple cone); three peptides that cause paralysis in fish were purified and characterized from milked venom.
Type Text
Publisher American Society for Biochemistry and Molecular Biology (ASBMB)
Volume 270
Issue 38
First Page 22361
Last Page 22367
Subject Conotoxins; Conus peptides; Conus purpurascens; Purple cone snail
Subject LCSH Conus; Marine toxins; Nicotinic receptors -- Antagonists
Language eng
Bibliographic Citation Hopkins, C., Grilley, M., Miller, C., Shon, K.-J., Cruz, L. J., Gray, W. R., Dykert, J., Rivier, J., Yoshikami, D., & Olivera, B. M. (1995). New family of Conus peptides targeted to the nicotinic acetylcholine receptor. Journal of Biological Chemistry, 270(38), 22361-7.
Rights Management (c)American Society for Biochemistry and Molecular Biology (ASBMB) http://www.asbmb.org/
Format Medium application/pdf
Format Extent 269,858 bytes
Identifier ir-main,8342
ARK ark:/87278/s60z7mp7
Setname ir_uspace
ID 704923
Reference URL https://collections.lib.utah.edu/ark:/87278/s60z7mp7
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