Publication Type |
Journal Article |
School or College |
College of Science |
Department |
Biology |
Creator |
Jorgensen, Erik |
Other Author |
Hartwieg, Erika; Yook, Karen; Horvitz, H. R. |
Title |
Genetic screens for synaptic function mutants in the nematode C. elegans |
Date |
1996 |
Description |
The synapse is the site of a remarkable conversion of electrical signals into chemical signals. This conversion takes place when a depolarizing impulse enters the axon terminal and opens voltage-sensitive calcium channels; calcium then flows into the cell and initiates the fusion of synaptic vesicles with the plasma membrane. The precise mechanisms of synaptic vesicle dynamics remains a mystery. We would like to understand the specialized molecular machinery that is required to dock and prepare vesicles for release, fuse the vesicular and plasma membranes, and finally to recycle vesicular components to regenerate mature synaptic vesicles. |
Type |
Text |
Publisher |
Society for Neuroscience |
First Page |
217 |
Last Page |
226 |
Subject |
Vesicle; Neurotransmission; Cell |
Language |
eng |
Bibliographic Citation |
Jorgensen, E. M., Hartwieg, E., Yook, K., & Horvitz, H. R. (1996). Genetic screens for synaptic function mutants in the nematode C. elegans, in Basic Neuroscience in Invertebrates. Neuroscience International Symposium, 217-26. |
Rights Management |
(c) Society for Neuroscience http://www.jneurosci.org/ |
Format Medium |
application/pdf |
Format Extent |
6,092,695 bytes |
Identifier |
ir-main,6321 |
ARK |
ark:/87278/s6jw8z2z |
Setname |
ir_uspace |
ID |
703388 |
Reference URL |
https://collections.lib.utah.edu/ark:/87278/s6jw8z2z |