| Publication Type |
Journal Article |
| School or College |
College of Science |
| Department |
Biology |
| Creator |
Jorgensen, Erik |
| Other Author |
Nonet, Michael L.; Holgado, Andrea M.; Brewer, Faraha; Serpe, Craig J.; Norbeck, Betty A.; Holleran, Julianne; Wei, Liping; Hartweig, Erika; Alfonso, Aixa |
| Title |
UNC-11, a Caenorhabditis elegans AP180 homologue, regulates the size and protein composition of synaptic vesicles |
| Date |
1999 |
| Description |
The unc-11 gene of Caenorhabditis elegans encodes multiple isoforms of a protein homologous to the mammalian brain-specific clathrin-adaptor protein AP180. The UNC-11 protein is expressed at high levels in the nervous system and at lower levels in other tissues. In neurons, UNC-11 is enriched at presynaptic terminals but is also present in cell bodies. unc-11 mutants are defective in two aspects of synaptic vesicle biogenesis. |
| Type |
Text |
| Publisher |
American Society for Cell Biology |
| Volume |
10 |
| Issue |
1 |
| First Page |
2343 |
| Last Page |
2360 |
| Subject |
Caenorhabditis elegans; Synaptic vesicles; unc-11; Synaptobrevin; Endocytosis |
| Subject LCSH |
Nematodes -- Genetics; Neurotransmitter receptors |
| Language |
eng |
| Bibliographic Citation |
Nonet, M. L., Holgado, A. M., Brewer, F., Serpe, C. J., Norbeck, B. A., Holleran, J., Wei, L., Hartweig, E., Jorgensen, E. M., & Alfonso, A. (1999). UNC-11, a Caenorhabditis elegans AP180 homologue, regulates the size and protein composition of synaptic vesicles. Molecular Biology of the Cell, 10(1), 2343-60. |
| Rights Management |
(c)American Society for Cell Biology http://www.molbiolcell.org/ |
| Format Medium |
application/pdf |
| Format Extent |
1,243,996 bytes |
| Identifier |
ir-main,6313 |
| ARK |
ark:/87278/s60298s7 |
| Setname |
ir_uspace |
| ID |
703961 |
| Reference URL |
https://collections.lib.utah.edu/ark:/87278/s60298s7 |
