| Identifier |
Paraneoplastic_Anti-Hu_and_Anti-CV2_positive_ataxic_cerebellar_and_sensory_ganglionopathy_encephalitis |
| Title |
Paraneoplastic Anti-Hu and Anti-CV2 Positive Ataxic (Cerebellar and Sensory Ganglionopathy) Encephalitis |
| Creator |
Anuj Rastogi; Rahul Sharma; Gustavo Saposnik; Alexandra Muccilli |
| Affiliation |
(AR) Neurology, University of Toronto; (RS) Ophthalmology, University of Toronto; (GS) Neurology, University of Toronto; (AM) Neurology, University of Toronto |
| Subject |
Anti-CV2; Anti-Hu; Ataxia; Cerebellar Ataxia; Encephalitis; Nystagmus; Sensory Ganglionopathy |
| Description |
We describe a case of an elderly man with Non-small Cell Lung Cancer, presenting with paraneoplastic Anti-Hu and Anti-CV2 positive encephalitis. He had both cerebellar ataxia and sensory ataxia, likely from the paraneoplastic induced cerebellar degeneration and sensory ganglionopathy, respectively. We describe the patient history, examination findings, including pertinent oculomotor abnormalities, and general management for these kinds of patients. We further discuss paraneoplastic cerebellar degeneration and autoimmune encephalitis as it relates to ataxia. |
| Date |
2024-03 |
| References |
Amato AA, Ropper AH. Sensory Ganglionopathy. N Engl J Med. 2020 Oct 22;383(17):1657-1662. Aly R, Emmady PD. Paraneoplastic Cerebellar Degeneration. [Updated 2023 Jul 4]. In: StatPearls [Internet]. Treasure Island (FL): StatPearls Publishing; 2024 Jan. Glickstein M, Strata P, Voogd J. Cerebellum: history. Neuroscience. 2009 Sep 1;162(3):549-59. doi: 10.1016/j.neuroscience.2009.02.054. Epub 2009 Mar 9. Greenlee JE. Treatment of paraneoplastic cerebellar degeneration. Curr Treat Options Neurol. 2013 Apr;15(2):185-200. Leigh J, Zee D. Neurology of Eye Movements. Oxford University Press; 5th edition (July 2 2015). Wahed LA, Cho TA. Imaging of Central Nervous System Autoimmune, Paraneoplastic, and Neuro-rheumatologic Disorders. Continuum (Minneap Minn). 2023 Feb 1;29(1):255-291. |
| Language |
eng |
| Format |
application/pdf |
| Type |
Text |
| Collection |
Neuro-Ophthalmology Virtual Education Library: NOVEL https://NOVEL.utah.edu |
| Publisher |
North American Neuro-Ophthalmology Society |
| Holding Institution |
Spencer S. Eccles Health Sciences Library, University of Utah |
| Rights Management |
Copyright 2024. For further information regarding the rights to this collection, please visit: https://NOVEL.utah.edu/about/copyright |
| ARK |
ark:/87278/s6shatq1 |
| Setname |
ehsl_novel_novel |
| ID |
2456811 |
| Reference URL |
https://collections.lib.utah.edu/ark:/87278/s6shatq1 |
