T-superfamily of conotoxins

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Publication Type Journal Article
School or College College of Science
Department Biology
Creator Olivera, Baldomero M.
Other Author Walker, Craig S.; Steel, Douglas; Jacobsen, Richard B.; Lirazan, Marcelina B.; Cruz, Lourdes J.; Hooper, David; Shetty, Reshma; DelaCruz, Richard C.; Nielsen, Jacob S.; Zhou, Li Ming; Bandyopadhyay, Pradip; Craig, A. Grey
Title T-superfamily of conotoxins
Date 1999
Description We report the discovery and initial characterization of the T-superfamily of conotoxins. Eight different T-superfamily peptides from five Conus species were identified; they share a consensus signal sequence, and a conserved arrangement of cysteine residues (- -CC- -CC-). T-superfamily peptides were found expressed in venom ducts of all major feeding types of Conus; the results suggest that the T-superfamily will be a large and diverse group of peptides, widely distributed in the 500 different Conus species.
Type Text
Publisher American Society for Biochemistry and Molecular Biology (ASBMB)
Volume 274
Issue 43
First Page 30664
Last Page 30671
Subject Conotoxins; T-superfamily
Subject LCSH Conus; Marine toxins; Conus -- Genetics
Language eng
Bibliographic Citation Walker, C. S., Steel, D., Jacobsen, R. B., Lirazan, M. B., Cruz, L. J., Hooper, D., Shetty, R., DelaCruz, R. C., Nielsen, J. S., Zhou, L. M., Bandyopadhyay, P., Craig, A. G., & Olivera, B. M. (1999). T-superfamily of conotoxins. Journal of Biological Chenistry, 274(43), 30664-71.
Rights Management (c)American Society for Biochemistry and Molecular Biology (ASBMB) http://www.asbmb.org/
Format Medium application/pdf
Format Extent 327,076 bytes
Identifier ir-main,8382
ARK ark:/87278/s61c2fhg
Setname ir_uspace
ID 707154
Reference URL https://collections.lib.utah.edu/ark:/87278/s61c2fhg
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