Pupillary Syndrome

Intermittent dilation of the pupils may occur as a benign phenomenon in healthy young adults. In the absence of other third nerve signs, (eg, ptosis, diplopia, ophthalmoplegia), an isolated transient dilation of the pupil in an otherwise healthy adult is unlikely to represent a third nerve palsy. Transient dilation and irregularity of the pupils has been referred to as tadpole pupils. These may occur in patients with or without migraine.