| Publication Type |
video |
| School or College |
School of Medicine; College of Science |
| Department |
Human Genetics; Oncological Sciences; Biology |
| Program |
Institute of Human Genetics. Howard Hughes Medical Institute. |
| Creator |
Capecchi, Mario R. |
| Title |
Role of Hox genes in mediating the mammalian body plan |
| Description |
This is a 1 hour, 5 minutes, 28 seconds video of a lecture given by Mario Capecchi on the genetic analysis of the Hox complex, or Hox cluster and their role in embryogenesis. Using examples such as the development of the hindbrain (rhombencephalon), facial nerves, and hands Capecchi outlines the relationship of the location of a specific gene on a chromosome and its expression, both where it is expressed and when. By knocking out specific genes, it is possible to trace the mutations that result and to infer the function of the gene. |
| Type |
Image/MovingImage |
| Publisher |
University of Utah |
| Subject |
Transgenic mice; Gene targeting; Genetic engineering; Molecular genetics; Homeobox genes; Histology - Pathological; Gene expression; Gene regulation; Genotype; Phenotype |
| Subject MESH |
Genetic Research; Gene Targeting; Mice, Knockout; DNA Mutational Analysis; Recombination, Genetic; Ethics, Medical; Gene Expression Regulation, Developmental |
| Language |
eng |
| Rights Management |
(c) Mario R. Capecchi |
| Identifier |
ir-main,1826 |
| ARK |
ark:/87278/s6vx117h |
| Setname |
ir_uspace |
| ID |
707685 |
| Reference URL |
https://collections.lib.utah.edu/ark:/87278/s6vx117h |
