Figure 50: Anatomy and Physiology of the Saccadic Pathways

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Identifier gold_textbook_figures_050
Title Figure 50: Anatomy and Physiology of the Saccadic Pathways
Creator Daniel R. Gold, DO
Affiliation (DRG) Departments of Neurology, Ophthalmology, Neurosurgery, Otolaryngology - Head & Neck Surgery, Emergency Medicine, and Medicine, The Johns Hopkins School of Medicine, Baltimore, Maryland
Description When a saccade is desired (or reflexively triggered), signals project from the saccade-related cortical eye fields to the superior colliculus, which serves to integrate and relay commands to the saccade generating brainstem circuitry. The inferior cerebellar peduncle (ICP) carries climbing fibers to the dorsal vermis, which has an inhibitory influence over the Purkinje cells. These Purkinje cells normally inhibit the ipsilateral fastigial nucleus, and the fastigial nucleus sends excitatory fibers to the contralateral excitatory burst neuron (EBN)/inhibitory burst neuron (IBN) pair within the paramedian pontine reticular formation (PPRF). The IBN project contralaterally to inhibit the VIth nucleus to prevent unwanted saccades in this direction, while the EBN project ipsilaterally to excite the VIth nucleus to facilitate saccades in this direction (an example of reciprocal innervation).
Date 2022
References Gold D. (2022). Neuro-ophthalmology and neuro-otology : a case-based guide for clinicians and scientists. Springer International Publishing AG. Retrieved September 16 2022 from https://online.statref.com/p/1057?grpAlias=.
Language eng
Format image/jpeg
Type Image
Relation is Part of Neuro-Ophthalmology and Neuro-Otology: A Case-Based Guide for Clinicians and Scientists
Collection Neuro-Ophthalmology Virtual Education Library: Dan Gold Collection: https://novel.utah.edu/Gold/
Publisher North American Neuro-Ophthalmology Society
Holding Institution Spencer S. Eccles Health Sciences Library, University of Utah
Rights Management Copyright 2016. For further information regarding the rights to this collection, please visit: https://NOVEL.utah.edu/about/copyright
ARK ark:/87278/s6t74s00
File Name gold_textbook_figures_050.png
Setname ehsl_novel_gold
ID 2050030
Reference URL https://collections.lib.utah.edu/ark:/87278/s6t74s00
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