Publication Type |
Journal Article |
School or College |
College of Science |
Department |
Biology |
Creator |
Olivera, Baldomero M.; McIntosh, J. Michael; Hillyard, David R. |
Other Author |
Santos, Ameurfina D.; Cruz, Lourdes J. |
Title |
A-superfamily of conotoxins: structural and functional divergence |
Date |
2004-02-03 |
Description |
The generation of functional novelty in proteins encoded by a gene superfamily is seldom well documented. In this report, we define the A-conotoxin superfamily, which is widely expressed in venoms of the predatory cone snails (Conus), and show how gene products that diverge considerably in structure and function have arisen within the same superfamily. |
Type |
Text |
Publisher |
American Society for Biochemistry and Molecular Biology (ASBMB) |
Journal Title |
Journal of Biological Chemistry |
Volume |
279 |
Issue |
17 |
First Page |
17596 |
Last Page |
17606 |
DOI |
10.1074/jbc.M309654200 |
citatation_issn |
0021-9258 |
Subject |
Conotoxins; A-superfamily conotoxin |
Subject LCSH |
Conus; Marine toxins; Conus -- Genetics |
Language |
eng |
Bibliographic Citation |
Santos, A. D.; McIntosh, J. M.; Hillyard, D. R.; Cruz, L. J.; Olivera, B. M. (2004). A-superfamily of conotoxins: structural and functional divergence. Journal of Bilogical Chemistry, 279(17), 17596-606. |
Rights Management |
(c)American Society for Biochemistry and Molecular Biology (ASBMB) http://www.asbmb.org/ |
Format Medium |
application/pdf |
Format Extent |
926,310 bytes |
Identifier |
ir-main,8432 |
ARK |
ark:/87278/s6np2nqb |
Setname |
ir_uspace |
ID |
704360 |
Reference URL |
https://collections.lib.utah.edu/ark:/87278/s6np2nqb |