Coughing It Up to Giant Cell Arteritis

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Identifier Zerpa_Smith_GCA_NOVEL_Submission
Title Coughing It Up to Giant Cell Arteritis
Creator Ethan Zerpa; Stacy V Smith
Affiliation (EZ) School of Osteopathic Medicine, Rowan University; (SVS) Neurosciences Center, Houston Methodist
Subject Cough; Giant Cell Arteritis; Large Vessel Vasculities
Description 71-year-old with cough, acute monocular diplopia, and bilateral blurred vision lasting eight days. ESR >130 mm/hr. FDG-PET with increased radiotracer activity in the thoracic aorta and branches with hyperintensity extending into the vessels of the neck consistent with giant cell arteritis (GCA). GCA is confirmed by temporal artery biopsy (TAB), though patients with large vessel involvement may have negative TAB and require imaging. Pulmonary sequelae is uncommon and cough may be secondary to vagal nerve stimulation from vasculitis in the aortic arch and branches. Inflammatory markers and clinical imaging are important in patients presenting with unremitting cough and visual manifestations.
Date 2024-10
References 1) Tomelleri A, Campochiaro C, Sartorelli S, Farina N, Baldissera E, Dagna L. Presenting features and outcomes of cranial-limited and large-vessel giant cell arteritis: a retrospective cohort study. Scand J Rheumatol. 2022;51(1):59-66. doi:10.1080/03009742.2021.1889025. 2) Azzam O, Hubble D, Prentice D. Cough as a clinical manifestation of large vessel vasculitis. Intern Med J. 2022;52(3):488-490. doi:10.1111/imj.15710. 3) Salahuddin M, Sabath BF. Giant Cell Arteritis as an Uncommon Cause of Chronic Cough: A Case Report. Am J Case Rep. 2021;22:e932945. Published 2021 Oct 14. doi:10.12659/AJCR.932945. 4) Mesquita A, Camara L, Patrício C, Brotas V. Boundaries of a systemic disease: a protean presentation of giant cell arteritis. BMJ Case Rep. 2020;13(3):e232234. Published 2020 Mar 25. doi:10.1136/bcr-2019-232234. 5) Robblee J, Singh RH. Headache in the Older Population: Causes, Diagnoses, and Treatments. Curr Pain Headache Rep. 2020;24(7):34. Published 2020 May 29. doi:10.1007/s11916-020-00866-8
Language eng
Format application/pdf
Format Creation Microsoft PowerPoint
Type Text
Collection Neuro-Ophthalmology Virtual Education Library: NOVEL https://NOVEL.utah.edu
Publisher North American Neuro-Ophthalmology Society
Holding Institution Spencer S. Eccles Health Sciences Library, University of Utah
Rights Management Copyright 2024. For further information regarding the rights to this collection, please visit: https://NOVEL.utah.edu/about/copyright
ARK ark:/87278/s6cxvrcn
Setname ehsl_novel_novel
ID 2546560
Reference URL https://collections.lib.utah.edu/ark:/87278/s6cxvrcn
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