(TD) (SG) Neurology, University of Missouri--Kansas City
Subject
B1; Korsakoff; Nystagmus; Thiamine; Wernicke
Description
This is a narrated powerpoint presentation about the neurological and neuro-ophthalmic presentations of thiamine deficiency. The clinical manifestations are reviewed. Basic biochemistry is briefly discussed. Management and diagnosis are explored.
Date
2024-09
References
Glen L Xiong, M. (2023a, September 27). Wernicke-Korsakoff syndrome. Practice Essentials, Background, Etiology. https://emedicine.medscape.com/article/288379-overview?form=fpf Isen DR, Kline LB. Neuro-ophthalmic Manifestations of Wernicke Encephalopathy. Eye Brain. 2020 Jun 30;12:49-60. doi: 10.2147/EB.S234078. PMID: 32636690; PMCID: PMC7335288. Palm A, Vataja R, Talaslahti T, Ginters M, Kautiainen H, Elonheimo H, Suvisaari J, Lindberg N, Koponen H. Incidence and mortality of alcohol-related dementia and Wernicke-Korsakoff syndrome: A nationwide register study. Int J Geriatr Psychiatry. 2022 Aug;37(8):10.1002/gps.5775. doi: 10.1002/gps.5775. PMID: 35789035; PMCID: PMC9546078. Wernicke-Korsakoff Syndrome: Wernicke's encephalopathy. National Organization for Rare Disorders. (2023, June 23). https://rarediseases.org/rare-diseases/wernicke-korsakoff-syndrome/#related-disorders What is nystagmus?. OasisEye Specialists. (2023, September 20). https://oasiseye.id/what-is-nystagmus/ Wiley KD, Gupta M. Vitamin B1 (Thiamine) Deficiency. [Updated 2023 Jul 17]. In: StatPearls [Internet]. Treasure Island (FL): StatPearls Publishing; 2024 Jan-. Available from: https://www.ncbi.nlm.nih.gov/books/NBK537204/