Publication Type |
Journal Article |
School or College |
College of Science |
Department |
Biology |
Creator |
Olivera, Baldomero M. |
Other Author |
Ferro, A. M.; McElwain, M. C. |
Title |
Poly(ADP-ribosylation) of DNA topoisomerase I: a nuclear response to DNA-strand interruptions |
Date |
1984 |
Description |
DNA in eukaryotic chromosomes is organized differently from prokaryotic DNA. It seems highly probable that mechanistic adjustments have been made in macromolecular DNA metabolism as a consequence of the chromatin structure of the eukaryotic chromosome (Igo-Kemenes et al. 1982)). This paper deals with an enzyme from eukaryotes, poly(ADP-ribose) synthetase, which may have a role in chromatin metabolism, and, in particular, we focus on the interaction between this enzyme and another enzyme that affects the structure of DNA, type-I DNA topoisomerase. |
Type |
Text |
Publisher |
Cold Spring Harbor Lab Press |
Volume |
49 |
First Page |
683 |
Last Page |
690 |
Subject |
Poly(ADP-ribosylation); Poly(ADP-ribose) synthetase; DNA strand interruption |
Subject LCSH |
DNA topoisomerases; ADP-ribosylation; DNA repair; DNA -- Metabolism; Chromatin; Drosophila -- Genetics |
Language |
eng |
Bibliographic Citation |
Ferro, A. M., McElwain, M. C., & Olivera, B. M. (1984). Poly(ADP-ribosylation) of DNA topoisomerase I: a nuclear response to DNA-strand interruptions. Cold Spring Harbor Symposia on Quantitative Biology, 49, 683-90. |
Rights Management |
(c) Cold Spring Harbor Laboratory Press-CSHL Press |
Format Medium |
application/pdf |
Format Extent |
4,154,165 bytes |
Identifier |
ir-main,8200 |
ARK |
ark:/87278/s6j96qz3 |
Setname |
ir_uspace |
ID |
706591 |
Reference URL |
https://collections.lib.utah.edu/ark:/87278/s6j96qz3 |