| Publication Type |
Journal Article |
| School or College |
College of Health |
| Department |
Nutrition |
| Creator |
Symons, John David |
| Other Author |
Zaid, Ussama B.; Athanassious, Christian N.; Mullick, Adam E.; Lentz, Steven R.; Rutledge, John C. |
| Title |
Influence of folate on arterial permeability and stiffness in the absence or presence of hyperhomocysteinemia |
| Date |
2006 |
| Description |
Elevation of plasma total homocysteine (tHcy) is associated with an increased risk of cardiovascular disease, but the underlying mechanisms are not well understood.1 Worldwide, the most common cause of mild hyperhomocysteinemia (HHcy) is deficiency of folate.2,3 Some4-8 but not all9,10 studies suggest that folate deficiency contributes to cardiovascular disease in a manner that is independent of its ability to elevate plasma tHcy.11 We have reported that HHcy evoked by folate depletion increases arterial permeability and stiffness in rats.12 |
| Type |
Text |
| Publisher |
American Heart Association |
| Volume |
26 |
| Issue |
4 |
| First Page |
814 |
| Last Page |
818 |
| Subject |
Cystathionine B-synthase; Carotid artery; Aorta; Cardiovascular risk factors; Folate; Hyperhomocysteinemia; Arterial permeability; Arterial stiffness |
| Subject LCSH |
Cardiovascular system -- Diseases -- Risk factors; Folic acid deficiency |
| Language |
eng |
| Bibliographic Citation |
Symons, J. D., Zaid, U. B., Athanassious, C. N., Mullick, A. E., Lentz, S. R., & Rutledge J.C. (2006). Influence of folate on arterial permeability and stiffness in the absence or presence of hyperhomocysteinemia. Arteriosclerosis, Thrombosis, and Vascular Biology, 26(4), 814-8. |
| Rights Management |
(c)American Heart Association http://www.ahajournals.org/ |
| Format Medium |
application/pdf |
| Format Extent |
353,523 bytes |
| Identifier |
ir-main,1579 |
| ARK |
ark:/87278/s67d3ch7 |
| Setname |
ir_uspace |
| ID |
704753 |
| Reference URL |
https://collections.lib.utah.edu/ark:/87278/s67d3ch7 |
