| Publication Type |
Journal Article |
| School or College |
College of Science |
| Department |
Biology |
| Creator |
Jorgensen, Erik |
| Other Author |
Harris, Todd W.; Hartwieg, Erika; Horvitz, H. Robert |
| Title |
Mutations in synaptojanin disrupt synaptic vesicle recycling |
| Date |
2000 |
| Description |
Synaptojanin is a polyphosphoinositide phosphatase that is found at synapses and binds to proteins implicated in endocytosis. For these reasons, it has been proposed that synaptojanin is involved in the recycling of synaptic vesicles. Here, we demonstrate that the unc-26 gene encodes the Caenorhabditis elegans ortholog of synaptojanin. unc-26 mutants exhibit defects in vesicle trafficking in several tissues, but most defects are found at synaptic termini. |
| Type |
Text |
| Publisher |
Rockefeller University Press |
| Volume |
150 |
| Issue |
3 |
| First Page |
589 |
| Last Page |
600 |
| Language |
eng |
| Bibliographic Citation |
Harris, T. W., Hartwieg, E., Horvitz, H. R., & Jorgensen, E. (2000). Mutations in synaptojanin disrupt synaptic vesicle recycling. Journal of Cell Biology, 150(3), 589-600. |
| Rights Management |
(c)T. W. Harris, E. Hartwieg, H. R. Horvitz, & E. Jorgensen http://www.jcb.org/ |
| Format Medium |
application/pdf |
| Format Extent |
902,977 bytes |
| Identifier |
ir-main,6307 |
| ARK |
ark:/87278/s63n2mjc |
| Setname |
ir_uspace |
| ID |
703230 |
| Reference URL |
https://collections.lib.utah.edu/ark:/87278/s63n2mjc |
