Re-Treatment With Ethambutol After Toxic Optic Neuropathy.

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Title Re-Treatment With Ethambutol After Toxic Optic Neuropathy.
Creator Marc A. Bouffard; Ruvandhi R. Nathavitharana; David S. Yassa; Nurhan Torun
Affiliation Department of Neurology (MAB, NT), Beth Israel Deaconess Medical Center, Boston, Massachusetts; Division of Infectious Disease (RRN, DY), Department of Medicine, Beth Israel Deaconess Medical Center, Boston, Massachusetts; and Division of Ophthalmology (NT), Department of Surgery, Beth Israel Deaconess Medical Center, Boston, Massachusetts
Abstract There are no data in the literature regarding the safety of re-treatment with ethambutol for recurrent mycobacterial infection after prior ethambutol-induced optic neuropathy. We describe a patient who developed optic neuropathy attributed to ethambutol, recovered fully after drug withdrawal, and tolerated a 14-month long re-treatment 10 years later without developing recurrent optic neuropathy.
Subject Antitubercular Agents / administration & dosage; Antitubercular Agents / adverse effects; Dose-Response Relationship, Drug; Ethambutol / administration & dosage; Ethambutol / adverse effects; Female; Humans; Middle Aged; Mycobacterium avium Complex / isolation & purification; Mycobacterium avium-intracellulare Infection / drug therapy; Mycobacterium avium-intracellulare Infection / microbiology; Optic Nerve Diseases / chemically induced; Optic Nerve Diseases / diagnosis; Retinal Ganglion Cells / pathology; Retreatment
OCR Text Show
Date 2017-03
Language eng
Format application/pdf
Type Text
Publication Type Journal Article
Collection Neuro-Ophthalmology Virtual Education Library: Journal of Neuro-Ophthalmology Archives: https://novel.utah.edu/jno/
Publisher Lippincott, Williams & Wilkins
Holding Institution Spencer S. Eccles Health Sciences Library, University of Utah
Rights Management © North American Neuro-Ophthalmology Society
ARK ark:/87278/s6b3218d
Setname ehsl_novel_jno
ID 1353376
Reference URL https://collections.lib.utah.edu/ark:/87278/s6b3218d
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