Title |
Re-Treatment With Ethambutol After Toxic Optic Neuropathy. |
Creator |
Marc A. Bouffard; Ruvandhi R. Nathavitharana; David S. Yassa; Nurhan Torun |
Affiliation |
Department of Neurology (MAB, NT), Beth Israel Deaconess Medical Center, Boston, Massachusetts; Division of Infectious Disease (RRN, DY), Department of Medicine, Beth Israel Deaconess Medical Center, Boston, Massachusetts; and Division of Ophthalmology (NT), Department of Surgery, Beth Israel Deaconess Medical Center, Boston, Massachusetts |
Abstract |
There are no data in the literature regarding the safety of re-treatment with ethambutol for recurrent mycobacterial infection after prior ethambutol-induced optic neuropathy. We describe a patient who developed optic neuropathy attributed to ethambutol, recovered fully after drug withdrawal, and tolerated a 14-month long re-treatment 10 years later without developing recurrent optic neuropathy. |
Subject |
Antitubercular Agents / administration & dosage; Antitubercular Agents / adverse effects; Dose-Response Relationship, Drug; Ethambutol / administration & dosage; Ethambutol / adverse effects; Female; Humans; Middle Aged; Mycobacterium avium Complex / isolation & purification; Mycobacterium avium-intracellulare Infection / drug therapy; Mycobacterium avium-intracellulare Infection / microbiology; Optic Nerve Diseases / chemically induced; Optic Nerve Diseases / diagnosis; Retinal Ganglion Cells / pathology; Retreatment |
Date |
2017-03 |
Language |
eng |
Format |
application/pdf |
Type |
Text |
Publication Type |
Journal Article |
Collection |
Neuro-Ophthalmology Virtual Education Library: Journal of Neuro-Ophthalmology Archives: https://novel.utah.edu/jno/ |
Publisher |
Lippincott, Williams & Wilkins |
Holding Institution |
Spencer S. Eccles Health Sciences Library, University of Utah |
Rights Management |
© North American Neuro-Ophthalmology Society |
ARK |
ark:/87278/s6b3218d |
Setname |
ehsl_novel_jno |
ID |
1353376 |
Reference URL |
https://collections.lib.utah.edu/ark:/87278/s6b3218d |